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Table 2 Correlations between CSF cyclic nucleotide levels and clinical and pathological markers of AD

From: Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression

  CSF cGMP CSF cAMP
  r s p r s p
CSF Aβ42 0.15 0.09 0.056 0.5183
CSF tau –0.28 0.001 –0.067 0.438
MMSE score 0.17 0.046 –0.047 0.59
  1. Correlation coefficients (r s) and p values calculated using Spearman’s rank correlation analysis. Statistically significant results depicted in bold
  2. AD Alzheimer’s disease, cAMP cyclic adenosine-3',5'-monophosphate, cGMP cyclic guanosine-3',5'-monophosphate, CSF cerebrospinal fluid, MMSE mini-mental state examination