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Table 2 Correlations between CSF cyclic nucleotide levels and clinical and pathological markers of AD

From: Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression

 

CSF cGMP

CSF cAMP

 

r s

p

r s

p

CSF Aβ42

0.15

0.09

0.056

0.5183

CSF tau

–0.28

0.001

–0.067

0.438

MMSE score

0.17

0.046

–0.047

0.59

  1. Correlation coefficients (r s) and p values calculated using Spearman’s rank correlation analysis. Statistically significant results depicted in bold
  2. AD Alzheimer’s disease, cAMP cyclic adenosine-3',5'-monophosphate, cGMP cyclic guanosine-3',5'-monophosphate, CSF cerebrospinal fluid, MMSE mini-mental state examination