TY - JOUR AU - Conti, M. AU - Beavo, J. PY - 2007 DA - 2007// TI - Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling JO - Annu Rev Biochem. VL - 76 UR - https://doi.org/10.1146/annurev.biochem.76.060305.150444 DO - 10.1146/annurev.biochem.76.060305.150444 ID - Conti2007 ER - TY - JOUR AU - Lu, Y. F. AU - Kandel, E. R. AU - Hawkins, R. D. PY - 1999 DA - 1999// TI - Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus JO - J Neurosci VL - 19 ID - Lu1999 ER - TY - JOUR AU - Silva, A. J. AU - Kogan, J. H. AU - Frankland, P. W. AU - Kida, S. PY - 1998 DA - 1998// TI - CREB and memory JO - Annu Rev Neurosci. VL - 21 UR - https://doi.org/10.1146/annurev.neuro.21.1.127 DO - 10.1146/annurev.neuro.21.1.127 ID - Silva1998 ER - TY - STD TI - Sheng M, Sabatini BL, Südhof TC. Synapses and Alzheimer's disease. Cold Spring Harb Perspect Biol. 2012;4(5):1-2. ID - ref4 ER - TY - JOUR AU - Querfurth, H. W. AU - LaFerla, F. M. PY - 2010 DA - 2010// TI - Alzheimer's disease JO - N Engl J Med VL - 362 UR - https://doi.org/10.1056/NEJMra0909142 DO - 10.1056/NEJMra0909142 ID - Querfurth2010 ER - TY - JOUR AU - Saura, C. A. AU - Valero, J. PY - 2011 DA - 2011// TI - The role of CREB signaling in Alzheimer's disease and other cognitive disorders JO - Rev Neurosci VL - 22 UR - https://doi.org/10.1515/rns.2011.018 DO - 10.1515/rns.2011.018 ID - Saura2011 ER - TY - JOUR AU - Bender, A. T. AU - Beavo, J. A. PY - 2006 DA - 2006// TI - Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use JO - Pharmacol Rev VL - 58 UR - https://doi.org/10.1124/pr.58.3.5 DO - 10.1124/pr.58.3.5 ID - Bender2006 ER - TY - JOUR AU - Staay, F. J. AU - Rutten, K. AU - Bärfacker, L. AU - Devry, J. AU - Erb, C. AU - Heckroth, H. AU - Karthaus, D. AU - Tersteegen, A. AU - Kampen, M. AU - Blokland, A. PY - 2008 DA - 2008// TI - The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents JO - Neuropharmacology VL - 55 UR - https://doi.org/10.1016/j.neuropharm.2008.07.005 DO - 10.1016/j.neuropharm.2008.07.005 ID - Staay2008 ER - TY - JOUR AU - Kroker, K. S. AU - Mathis, C. AU - Marti, A. AU - Cassel, J. C. AU - Rosenbrock, H. AU - Dorner-Ciossek, C. PY - 2014 DA - 2014// TI - PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition JO - Neurobiol Aging VL - 35 UR - https://doi.org/10.1016/j.neurobiolaging.2014.03.023 DO - 10.1016/j.neurobiolaging.2014.03.023 ID - Kroker2014 ER - TY - JOUR AU - Jancic, D. AU - Lopez de Armentia, M. AU - Valor, L. M. AU - Olivares, R. AU - Barco, A. PY - 2009 DA - 2009// TI - Inhibition of cAMP response element-binding protein reduces neuronal excitability and plasticity, and triggers neurodegeneration JO - Cereb Cortex VL - 19 UR - https://doi.org/10.1093/cercor/bhp004 DO - 10.1093/cercor/bhp004 ID - Jancic2009 ER - TY - JOUR AU - Bonkale, W. L. AU - Winblad, B. AU - Ravid, R. AU - Cowburn, R. F. PY - 1995 DA - 1995// TI - Reduced nitric oxide responsive soluble guanylyl cyclase activity in the superior temporal cortex of patients with Alzheimer's disease JO - Neurosci Lett VL - 187 UR - https://doi.org/10.1016/0304-3940(95)11323-O DO - 10.1016/0304-3940(95)11323-O ID - Bonkale1995 ER - TY - JOUR AU - Jack, C. R. AU - Knopman, D. S. AU - Jagust, W. J. AU - Shaw, L. M. AU - Aisen, P. S. AU - Weiner, M. W. AU - Petersen, R. C. AU - Trojanowski, J. Q. PY - 2010 DA - 2010// TI - Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade JO - Lancet Neurol VL - 9 UR - https://doi.org/10.1016/S1474-4422(09)70299-6 DO - 10.1016/S1474-4422(09)70299-6 ID - Jack2010 ER - TY - JOUR AU - Dupiereux, I. AU - Zorzi, W. AU - Quadrio, I. AU - Perret-Liaudet, A. AU - Kovacs, G. G. AU - Heinen, E. AU - Elmoualij, B. PY - 2009 DA - 2009// TI - Creutzfeldt-jakob, Parkinson, Lewy body dementia and Alzheimer diseases: from diagnosis to therapy JO - Cent Nerv Syst Agents Med Chem VL - 9 UR - https://doi.org/10.2174/187152409787601950 DO - 10.2174/187152409787601950 ID - Dupiereux2009 ER - TY - STD TI - Ugarte A, Gil-Bea F, García-Barroso C, Cedazo-Minguez A, Ramírez MJ, Franco R, García-Osta A, Oyarzabal J, Cuadrado-Tejedor M. Decreased levels of cGMP in CSF are associated with cognitive decline and amyloid pathology in Alzheimer's disease. Neuropathol Appl Neurobiol. 2015;41(4):471-82. ID - ref14 ER - TY - JOUR AU - Martínez, M. AU - Fernández, E. AU - Frank, A. AU - Guaza, C. AU - Fuente, M. AU - Hernanz, A. PY - 1999 DA - 1999// TI - Increased cerebrospinal fluid cAMP levels in Alzheimer's disease JO - Brain Res VL - 846 UR - https://doi.org/10.1016/S0006-8993(99)01981-2 DO - 10.1016/S0006-8993(99)01981-2 ID - Martínez1999 ER - TY - JOUR AU - Geda, Y. E. AU - Schneider, L. S. AU - Gitlin, L. N. AU - Miller, D. S. AU - Smith, G. S. AU - Bell, J. AU - Evans, J. AU - Lee, M. AU - Porsteinsson, A. AU - Lanctôt, K. L. PY - 2013 DA - 2013// TI - Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future JO - Alzheimers Dement VL - 9 UR - https://doi.org/10.1016/j.jalz.2012.12.001 DO - 10.1016/j.jalz.2012.12.001 ID - Geda2013 ER - TY - JOUR AU - Mesulam, M. M. PY - 1998 DA - 1998// TI - From sensation to cognition JO - Brain VL - 121 UR - https://doi.org/10.1093/brain/121.6.1013 DO - 10.1093/brain/121.6.1013 ID - Mesulam1998 ER - TY - STD TI - Mirza SS, Wolters FJ, Swanson SA, Koudstaal PJ, Hofman A, Tiemeier H, Ikram MA. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study. Lancet Psychiatry. 2016;3(7):628-35. ID - ref18 ER - TY - JOUR AU - Frisardi, V. AU - Panza, F. AU - Farooqui, A. A. PY - 2011 DA - 2011// TI - Late-life depression and Alzheimer's disease: the glutamatergic system inside of this mirror relationship JO - Brain Res Rev VL - 67 UR - https://doi.org/10.1016/j.brainresrev.2011.04.003 DO - 10.1016/j.brainresrev.2011.04.003 ID - Frisardi2011 ER - TY - JOUR AU - Reierson, G. W. AU - Guo, S. AU - Mastronardi, C. AU - Licinio, J. AU - Wong, M. L. PY - 2011 DA - 2011// TI - cGMP signaling, phosphodiesterases and major depressive disorder JO - Curr Neuropharmacol VL - 9 UR - https://doi.org/10.2174/157015911798376271 DO - 10.2174/157015911798376271 ID - Reierson2011 ER - TY - JOUR AU - Folstein, M. F. AU - Folstein, S. E. AU - McHugh, P. R. PY - 1975 DA - 1975// TI - "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician JO - J Psychiatr Res VL - 12 UR - https://doi.org/10.1016/0022-3956(75)90026-6 DO - 10.1016/0022-3956(75)90026-6 ID - Folstein1975 ER - TY - JOUR AU - Albert, M. S. AU - DeKosky, S. T. AU - Dickson, D. AU - Dubois, B. AU - Feldman, H. H. AU - Fox, N. C. AU - Gamst, A. AU - Holtzman, D. M. AU - Jagust, W. J. AU - Petersen, R. C. PY - 2011 DA - 2011// TI - The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease JO - Alzheimers Dement VL - 7 UR - https://doi.org/10.1016/j.jalz.2011.03.008 DO - 10.1016/j.jalz.2011.03.008 ID - Albert2011 ER - TY - JOUR AU - McKhann, G. M. AU - Knopman, D. S. AU - Chertkow, H. AU - Hyman, B. T. AU - Jack, C. R. AU - Kawas, C. H. AU - Klunk, W. E. AU - Koroshetz, W. J. AU - Manly, J. J. AU - Mayeux, R. PY - 2011 DA - 2011// TI - The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease JO - Alzheimers Dement VL - 7 UR - https://doi.org/10.1016/j.jalz.2011.03.005 DO - 10.1016/j.jalz.2011.03.005 ID - McKhann2011 ER - TY - JOUR AU - Sperling, R. A. AU - Aisen, P. S. AU - Beckett, L. A. AU - Bennett, D. A. AU - Craft, S. AU - Fagan, A. M. AU - Iwatsubo, T. AU - Jack, C. R. AU - Kaye, J. AU - Montine, T. J. PY - 2011 DA - 2011// TI - Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease JO - Alzheimers Dement VL - 7 UR - https://doi.org/10.1016/j.jalz.2011.03.003 DO - 10.1016/j.jalz.2011.03.003 ID - Sperling2011 ER - TY - JOUR AU - Brettschneider, J. AU - Petzold, A. AU - Schottle, D. AU - Claus, A. AU - Riepe, M. AU - Tumani, H. PY - 2006 DA - 2006// TI - The neurofilament heavy chain (NfH) in the cerebrospinal fluid diagnosis of Alzheimer's disease JO - Dement Geriatr Cogn Disord VL - 21 UR - https://doi.org/10.1159/000091436 DO - 10.1159/000091436 ID - Brettschneider2006 ER - TY - JOUR AU - Vanderstichele, H. AU - Kerschaver, E. AU - Hesse, C. AU - Davidsson, P. AU - Buyse, M. A. AU - Andreasen, N. AU - Minthon, L. AU - Wallin, A. AU - Blennow, K. AU - Vanmechelen, E. PY - 2000 DA - 2000// TI - Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma JO - Amyloid VL - 7 UR - https://doi.org/10.3109/13506120009146438 DO - 10.3109/13506120009146438 ID - Vanderstichele2000 ER - TY - JOUR AU - Vandermeeren, M. AU - Mercken, M. AU - Vanmechelen, E. AU - Six, J. AU - Voorde, A. AU - Martin, J. J. AU - Cras, P. PY - 1993 DA - 1993// TI - Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay JO - J Neurochem VL - 61 UR - https://doi.org/10.1111/j.1471-4159.1993.tb09823.x DO - 10.1111/j.1471-4159.1993.tb09823.x ID - Vandermeeren1993 ER - TY - BOOK PY - 2015 DA - 2015// TI - R. A Language and Environment for Statistical Computing PB - R Foundation for Statistical Computing CY - Vienna ID - ref28 ER - TY - JOUR AU - Muessel, C. AU - Lausser, L. AU - Maucher, M. AU - Kestler, H. PY - 2012 DA - 2012// TI - Multi-objective parameter selection for classifiers JO - J Stat Softw VL - 46 ID - Muessel2012 ER - TY - BOOK AU - Breiman, L. AU - Friedman, J. AU - Olshen, R. AU - Stone, C. PY - 1984 DA - 1984// TI - Classification and Regression Trees PB - Wadsworth and Brooks CY - Monterey ID - Breiman1984 ER - TY - JOUR AU - Selkoe, D. J. PY - 2002 DA - 2002// TI - Alzheimer's disease is a synaptic failure JO - Science VL - 298 UR - https://doi.org/10.1126/science.1074069 DO - 10.1126/science.1074069 ID - Selkoe2002 ER - TY - JOUR AU - Scheff, S. W. AU - Price, D. A. AU - Schmitt, F. A. AU - Mufson, E. J. PY - 2006 DA - 2006// TI - Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment JO - Neurobiol Aging VL - 27 UR - https://doi.org/10.1016/j.neurobiolaging.2005.09.012 DO - 10.1016/j.neurobiolaging.2005.09.012 ID - Scheff2006 ER - TY - JOUR AU - Malenka, R. C. AU - Bear, M. F. PY - 2004 DA - 2004// TI - LTP and LTD: an embarrassment of riches JO - Neuron VL - 44 UR - https://doi.org/10.1016/j.neuron.2004.09.012 DO - 10.1016/j.neuron.2004.09.012 ID - Malenka2004 ER - TY - JOUR AU - Bliss, T. V. AU - Collingridge, G. L. PY - 1993 DA - 1993// TI - A synaptic model of memory: long-term potentiation in the hippocampus JO - Nature VL - 361 UR - https://doi.org/10.1038/361031a0 DO - 10.1038/361031a0 ID - Bliss1993 ER - TY - JOUR AU - Collingridge, G. L. AU - Peineau, S. AU - Howland, J. G. AU - Wang, Y. T. PY - 2010 DA - 2010// TI - Long-term depression in the CNS JO - Nat Rev Neurosci VL - 11 UR - https://doi.org/10.1038/nrn2867 DO - 10.1038/nrn2867 ID - Collingridge2010 ER - TY - JOUR AU - Sanderson, T. M. AU - Sher, E. PY - 2013 DA - 2013// TI - The role of phosphodiesterases in hippocampal synaptic plasticity JO - Neuropharmacology. VL - 74 UR - https://doi.org/10.1016/j.neuropharm.2013.01.011 DO - 10.1016/j.neuropharm.2013.01.011 ID - Sanderson2013 ER - TY - JOUR AU - Kleppisch, T. AU - Feil, R. PY - 2009 DA - 2009// TI - cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour JO - Handb Exp Pharmacol. VL - 191 UR - https://doi.org/10.1007/978-3-540-68964-5_24 DO - 10.1007/978-3-540-68964-5_24 ID - Kleppisch2009 ER - TY - JOUR AU - Bonkale, W. L. AU - Cowburn, R. F. AU - Ohm, T. G. AU - Bogdanovic, N. AU - Fastbom, J. PY - 1999 DA - 1999// TI - A quantitative autoradiographic study of [3H]cAMP binding to cytosolic and particulate protein kinase A in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits JO - Brain Res VL - 818 UR - https://doi.org/10.1016/S0006-8993(98)01307-9 DO - 10.1016/S0006-8993(98)01307-9 ID - Bonkale1999 ER - TY - JOUR AU - García-Jiménez, A. AU - Cowburn, R. F. AU - Ohm, T. G. AU - Bogdanovic, N. AU - Winblad, B. AU - Fastbom, J. PY - 1999 DA - 1999// TI - Quantitative autoradiography of [3H]forskolin binding sites in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits JO - Brain Res VL - 850 UR - https://doi.org/10.1016/S0006-8993(99)02111-3 DO - 10.1016/S0006-8993(99)02111-3 ID - García-Jiménez1999 ER - TY - JOUR AU - Liang, Z. AU - Liu, F. AU - Grundke-Iqbal, I. AU - Iqbal, K. AU - Gong, C. X. PY - 2007 DA - 2007// TI - Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain JO - J Neurochem VL - 103 UR - https://doi.org/10.1111/j.1471-4159.2007.04942.x DO - 10.1111/j.1471-4159.2007.04942.x ID - Liang2007 ER - TY - JOUR AU - Domek-Łopacińska, K. U. AU - Strosznajder, J. B. PY - 2010 DA - 2010// TI - Cyclic GMP and nitric oxide synthase in aging and Alzheimer's disease JO - Mol Neurobiol VL - 41 UR - https://doi.org/10.1007/s12035-010-8104-x DO - 10.1007/s12035-010-8104-x ID - Domek-Łopacińska2010 ER - TY - JOUR AU - Blokland, A. AU - Schreiber, R. AU - Prickaerts, J. PY - 2006 DA - 2006// TI - Improving memory: a role for phosphodiesterases JO - Curr Pharm Des VL - 12 UR - https://doi.org/10.2174/138161206777698855 DO - 10.2174/138161206777698855 ID - Blokland2006 ER - TY - JOUR AU - Scott, B. R. PY - 2012 DA - 2012// TI - Cyclic AMP response element-binding protein (CREB) phosphorylation: a mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics JO - Biochem Pharmacol VL - 83 UR - https://doi.org/10.1016/j.bcp.2011.11.009 DO - 10.1016/j.bcp.2011.11.009 ID - Scott2012 ER - TY - JOUR AU - Lu, Y. F. AU - Hawkins, R. D. PY - 2002 DA - 2002// TI - Ryanodine receptors contribute to cGMP-induced late-phase LTP and CREB phosphorylation in the hippocampus JO - J Neurophysiol VL - 88 ID - Lu2002 ER - TY - JOUR AU - Thal, D. R. AU - Rüb, U. AU - Orantes, M. AU - Braak, H. PY - 2002 DA - 2002// TI - Phases of A beta-deposition in the human brain and its relevance for the development of AD JO - Neurology VL - 58 UR - https://doi.org/10.1212/WNL.58.12.1791 DO - 10.1212/WNL.58.12.1791 ID - Thal2002 ER - TY - JOUR AU - Braak, H. AU - Braak, E. PY - 1991 DA - 1991// TI - Neuropathological stageing of Alzheimer-related changes JO - Acta Neuropathol VL - 82 UR - https://doi.org/10.1007/BF00308809 DO - 10.1007/BF00308809 ID - Braak1991 ER - TY - JOUR AU - Jack, C. R. AU - Knopman, D. S. AU - Jagust, W. J. AU - Petersen, R. C. AU - Weiner, M. W. AU - Aisen, P. S. AU - Shaw, L. M. AU - Vemuri, P. AU - Wiste, H. J. AU - Weigand, S. D. PY - 2013 DA - 2013// TI - Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers JO - Lancet Neurol VL - 12 UR - https://doi.org/10.1016/S1474-4422(12)70291-0 DO - 10.1016/S1474-4422(12)70291-0 ID - Jack2013 ER - TY - JOUR AU - Yamamoto, M. AU - Götz, M. E. AU - Ozawa, H. AU - Luckhaus, C. AU - Saito, T. AU - Rösler, M. AU - Riederer, P. PY - 2000 DA - 2000// TI - Hippocampal level of neural specific adenylyl cyclase type I is decreased in Alzheimer's disease JO - Biochim Biophys Acta VL - 1535 UR - https://doi.org/10.1016/S0925-4439(00)00083-1 DO - 10.1016/S0925-4439(00)00083-1 ID - Yamamoto2000 ER - TY - JOUR AU - Kim, S. H. AU - Nairn, A. C. AU - Cairns, N. AU - Lubec, G. PY - 2001 DA - 2001// TI - Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease JO - J Neural Transm Suppl. VL - 61 ID - Kim2001 ER - TY - JOUR AU - Pérez-Torres, S. AU - Cortés, R. AU - Tolnay, M. AU - Probst, A. AU - Palacios, J. M. AU - Mengod, G. PY - 2003 DA - 2003// TI - Alterations on phosphodiesterase type 7 and 8 isozyme mRNA expression in Alzheimer's disease brains examined by in situ hybridization JO - Exp Neurol VL - 182 UR - https://doi.org/10.1016/S0014-4886(03)00042-6 DO - 10.1016/S0014-4886(03)00042-6 ID - Pérez-Torres2003 ER - TY - STD TI - Sierksma AS, van den Hove DL, Pfau F, Philippens M, Bruno O, Fedele E, Ricciarelli R, Steinbusch HW, Vanmierlo T, Prickaerts J. Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D. Neuropharmacology. 2014;77:120-30. ID - ref51 ER - TY - JOUR AU - Cowburn, R. F. AU - Marcusson, J. O. AU - Eriksson, A. AU - Wiehager, B. AU - O'Neill, C. PY - 1994 DA - 1994// TI - Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims JO - Brain Res VL - 633 UR - https://doi.org/10.1016/0006-8993(94)91552-0 DO - 10.1016/0006-8993(94)91552-0 ID - Cowburn1994 ER - TY - JOUR AU - Mizrachi, K. AU - Aricha, R. AU - Feferman, T. AU - Kela-Madar, N. AU - Mandel, I. AU - Paperna, T. AU - Miller, A. AU - Ben-Nun, A. AU - Berrih-Aknin, S. AU - Souroujon, M. C. PY - 2010 DA - 2010// TI - Involvement of phosphodiesterases in autoimmune diseases JO - J Neuroimmunol VL - 220 UR - https://doi.org/10.1016/j.jneuroim.2009.12.012 DO - 10.1016/j.jneuroim.2009.12.012 ID - Mizrachi2010 ER - TY - JOUR AU - Hebb, A. L. AU - Robertson, H. A. AU - Denovan-Wright, E. M. PY - 2004 DA - 2004// TI - Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms JO - Neuroscience VL - 123 UR - https://doi.org/10.1016/j.neuroscience.2003.11.009 DO - 10.1016/j.neuroscience.2003.11.009 ID - Hebb2004 ER - TY - JOUR AU - Belmaker, R. H. AU - Ebstein, R. P. AU - Biederman, J. AU - Stern, R. AU - Berman, M. AU - Praag, H. M. PY - 1978 DA - 1978// TI - The effect of L-dopa and propranolol on human CSF cyclic nucleotides JO - Psychopharmacology (Berl) VL - 58 UR - https://doi.org/10.1007/BF00427396 DO - 10.1007/BF00427396 ID - Belmaker1978 ER - TY - JOUR AU - Volicer, L. AU - Beal, M. F. AU - Direnfeld, L. K. AU - Marquis, J. K. AU - Albert, M. L. PY - 1986 DA - 1986// TI - CSF cyclic nucleotides and somatostatin in Parkinson's disease JO - Neurology VL - 36 UR - https://doi.org/10.1212/WNL.36.1.89 DO - 10.1212/WNL.36.1.89 ID - Volicer1986 ER - TY - JOUR AU - Oeckl, P. AU - Steinacker, P. AU - Lehnert, S. AU - Jesse, S. AU - Kretzschmar, H. A. AU - Ludolph, A. C. AU - Otto, M. AU - Ferger, B. PY - 2012 DA - 2012// TI - CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0032664 DO - 10.1371/journal.pone.0032664 ID - Oeckl2012 ER - TY - JOUR AU - Navarro, J. A. AU - Jiménez-Jiménez, F. J. AU - Molina, J. A. AU - Benito-León, J. AU - Cisneros, E. AU - Gasalla, T. AU - Ortí-Pareja, M. AU - Tallón-Barranco, A. AU - Bustos, F. AU - Arenas, J. PY - 1998 DA - 1998// TI - Cerebrospinal fluid cyclic guanosine 3'5' monophosphate levels in Parkinson's disease JO - J Neurol Sci VL - 155 UR - https://doi.org/10.1016/S0022-510X(97)00267-0 DO - 10.1016/S0022-510X(97)00267-0 ID - Navarro1998 ER - TY - JOUR AU - Reyes-Irisarri, E. AU - Markerink-Van Ittersum, M. AU - Mengod, G. AU - Vente, J. PY - 2007 DA - 2007// TI - Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains JO - Eur J Neurosci VL - 25 UR - https://doi.org/10.1111/j.1460-9568.2007.05589.x DO - 10.1111/j.1460-9568.2007.05589.x ID - Reyes-Irisarri2007 ER - TY - JOUR AU - Jin, F. AU - Gong, Q. H. AU - Xu, Y. S. AU - Wang, L. N. AU - Jin, H. AU - Li, F. AU - Li, L. S. AU - Ma, Y. M. AU - Shi, J. S. PY - 2014 DA - 2014// TI - Icariin, a phosphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling JO - Int J Neuropsychopharmacol VL - 17 UR - https://doi.org/10.1017/S1461145713001533 DO - 10.1017/S1461145713001533 ID - Jin2014 ER - TY - JOUR AU - Cuadrado-Tejedor, M. AU - Hervias, I. AU - Ricobaraza, A. AU - Puerta, E. AU - Pérez-Roldán, J. M. AU - García-Barroso, C. AU - Franco, R. AU - Aguirre, N. AU - García-Osta, A. PY - 2011 DA - 2011// TI - Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease JO - Br J Pharmacol VL - 164 UR - https://doi.org/10.1111/j.1476-5381.2011.01517.x DO - 10.1111/j.1476-5381.2011.01517.x ID - Cuadrado-Tejedor2011 ER - TY - JOUR AU - Puzzo, D. AU - Staniszewski, A. AU - Deng, S. X. AU - Privitera, L. AU - Leznik, E. AU - Liu, S. AU - Zhang, H. AU - Feng, Y. AU - Palmeri, A. AU - Landry, D. W. PY - 2009 DA - 2009// TI - Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse model JO - J Neurosci VL - 29 UR - https://doi.org/10.1523/JNEUROSCI.0864-09.2009 DO - 10.1523/JNEUROSCI.0864-09.2009 ID - Puzzo2009 ER - TY - JOUR AU - Sierksma, A. S. AU - Rutten, K. AU - Sydlik, S. AU - Rostamian, S. AU - Steinbusch, H. W. AU - Hove, D. L. AU - Prickaerts, J. PY - 2013 DA - 2013// TI - Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease JO - Neuropharmacology. VL - 64 UR - https://doi.org/10.1016/j.neuropharm.2012.06.048 DO - 10.1016/j.neuropharm.2012.06.048 ID - Sierksma2013 ER - TY - JOUR AU - Ikeda, M. AU - Sato, I. AU - Yuasa, T. AU - Miyatake, T. AU - Murota, S. PY - 1995 DA - 1995// TI - Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases JO - J Neural Transm Gen Sect VL - 100 UR - https://doi.org/10.1007/BF01276464 DO - 10.1007/BF01276464 ID - Ikeda1995 ER - TY - JOUR AU - Olesen, J. PY - 2010 DA - 2010// TI - Nitric oxide-related drug targets in headache JO - Neurotherapeutics VL - 7 UR - https://doi.org/10.1016/j.nurt.2010.03.006 DO - 10.1016/j.nurt.2010.03.006 ID - Olesen2010 ER - TY - JOUR AU - Iversen, H. K. AU - Olesen, J. AU - Tfelt-Hansen, P. PY - 1989 DA - 1989// TI - Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics JO - Pain. VL - 38 UR - https://doi.org/10.1016/0304-3959(89)90067-5 DO - 10.1016/0304-3959(89)90067-5 ID - Iversen1989 ER - TY - JOUR AU - Thomsen, L. L. AU - Kruuse, C. AU - Iversen, H. K. AU - Olesen, J. PY - 1994 DA - 1994// TI - A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks JO - Eur J Neurol VL - 1 UR - https://doi.org/10.1111/j.1468-1331.1994.tb00053.x DO - 10.1111/j.1468-1331.1994.tb00053.x ID - Thomsen1994 ER - TY - JOUR AU - Gallai, V. AU - Alberti, A. AU - Gallai, B. AU - Coppola, F. AU - Floridi, A. AU - Sarchielli, P. PY - 2003 DA - 2003// TI - Glutamate and nitric oxide pathway in chronic daily headache: evidence from cerebrospinal fluid JO - Cephalalgia VL - 23 UR - https://doi.org/10.1046/j.1468-2982.2003.00552.x DO - 10.1046/j.1468-2982.2003.00552.x ID - Gallai2003 ER - TY - JOUR AU - Baltrons, M. A. AU - Pedraza, C. E. AU - Heneka, M. T. AU - García, A. PY - 2002 DA - 2002// TI - Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells JO - Neurobiol Dis VL - 10 UR - https://doi.org/10.1006/nbdi.2002.0492 DO - 10.1006/nbdi.2002.0492 ID - Baltrons2002 ER - TY - JOUR AU - Sager, G. PY - 2004 DA - 2004// TI - Cyclic GMP, transporters JO - Neurochem Int VL - 45 UR - https://doi.org/10.1016/j.neuint.2004.03.017 DO - 10.1016/j.neuint.2004.03.017 ID - Sager2004 ER - TY - JOUR AU - Cramer, H. AU - Ng, L. K. AU - Chase, T. N. PY - 1973 DA - 1973// TI - Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease JO - Arch Neurol VL - 29 UR - https://doi.org/10.1001/archneur.1973.00490270079014 DO - 10.1001/archneur.1973.00490270079014 ID - Cramer1973 ER - TY - JOUR AU - Dranovsky, A. AU - Hen, R. PY - 2006 DA - 2006// TI - Hippocampal neurogenesis: regulation by stress and antidepressants JO - Biol Psychiatry VL - 59 UR - https://doi.org/10.1016/j.biopsych.2006.03.082 DO - 10.1016/j.biopsych.2006.03.082 ID - Dranovsky2006 ER - TY - JOUR AU - Videbech, P. AU - Ravnkilde, B. PY - 2004 DA - 2004// TI - Hippocampal volume and depression: a meta-analysis of MRI studies JO - Am J Psychiatry VL - 161 UR - https://doi.org/10.1176/appi.ajp.161.11.1957 DO - 10.1176/appi.ajp.161.11.1957 ID - Videbech2004 ER - TY - JOUR AU - Sheline, Y. I. AU - Wang, P. W. AU - Gado, M. H. AU - Csernansky, J. G. AU - Vannier, M. W. PY - 1996 DA - 1996// TI - Hippocampal atrophy in recurrent major depression JO - Proc Natl Acad Sci U S A VL - 93 UR - https://doi.org/10.1073/pnas.93.9.3908 DO - 10.1073/pnas.93.9.3908 ID - Sheline1996 ER - TY - JOUR AU - Higley, M. J. AU - Picciotto, M. R. PY - 2014 DA - 2014// TI - Neuromodulation by acetylcholine: examples from schizophrenia and depression JO - Curr Opin Neurobiol. VL - 29 UR - https://doi.org/10.1016/j.conb.2014.06.004 DO - 10.1016/j.conb.2014.06.004 ID - Higley2014 ER - TY - JOUR AU - Vente, J. PY - 2004 DA - 2004// TI - cGMP: a second messenger for acetylcholine in the brain? JO - Neurochem Int VL - 45 UR - https://doi.org/10.1016/j.neuint.2004.03.010 DO - 10.1016/j.neuint.2004.03.010 ID - Vente2004 ER - TY - JOUR AU - Davies, P. AU - Maloney, A. J. PY - 1976 DA - 1976// TI - Selective loss of central cholinergic neurons in Alzheimer's disease JO - Lancet VL - 2 UR - https://doi.org/10.1016/S0140-6736(76)91936-X DO - 10.1016/S0140-6736(76)91936-X ID - Davies1976 ER - TY - JOUR AU - Perry, E. K. AU - Tomlinson, B. E. AU - Blessed, G. AU - Perry, R. H. AU - Cross, A. J. AU - Crow, T. T. PY - 1981 DA - 1981// TI - Noradrenergic and cholinergic systems in senile dementia of Alzheimer type JO - Lancet VL - 2 UR - https://doi.org/10.1016/S0140-6736(81)90327-5 DO - 10.1016/S0140-6736(81)90327-5 ID - Perry1981 ER - TY - JOUR AU - Sapolsky, R. M. PY - 2000 DA - 2000// TI - Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders JO - Arch Gen Psychiatry VL - 57 UR - https://doi.org/10.1001/archpsyc.57.10.925 DO - 10.1001/archpsyc.57.10.925 ID - Sapolsky2000 ER - TY - JOUR AU - García-Barroso, C. AU - Ugarte, A. AU - Martínez, M. AU - Rico, A. J. AU - Lanciego, J. L. AU - Franco, R. AU - Oyarzabal, J. AU - Cuadrado-Tejedor, M. AU - García-Osta, A. PY - 2014 DA - 2014// TI - Phosphodiesterase inhibition in cognitive decline JO - J Alzheimers Dis. VL - 42 ID - García-Barroso2014 ER - TY - JOUR AU - Zhihui, Q. PY - 2013 DA - 2013// TI - Modulating nitric oxide signaling in the CNS for Alzheimer's disease therapy JO - Future Med Chem VL - 5 UR - https://doi.org/10.4155/fmc.13.111 DO - 10.4155/fmc.13.111 ID - Zhihui2013 ER -