Table 4 HRs (95% CIs) of the Australian National University Alzheimer’s Disease Risk Index and explained variance-weighted genetic risk scores upon cognitive transition

CN to MCI

1.07 (1.04–1.10)^c

1.05 (0.86–1.29)

1.07 (1.04–1.09)^c

1.03 (0.87–1.21)

CN to dementia

0.61 (0.33–1.13)

4.19 (1.72–10.2)^c

CN to death

1.03 (0.94–1.12)

0.70 (0.27–1.84)

1.02 (0.98–1.06)

0.89 (0.69–1.16)

MCI to CN

0.85 (0.11–6.79)

0.95 (0–181.21)

0.71 (0.50–1.00)

0.44 (0.12–1.54)

MCI to dementia

1.02 (0.94–1.10)

1.19 (0.76–1.85)

MCI to death

0.96 (0.83–1.11)

0.87 (0.29–2.63)

1.05 (0.98–1.12)

1.05 (0.65–1.71)

Dementia to death

0.99 (0.90–1.09)

0.78 (0.51–1.19)