Table 3 Associations between the Australian National University Alzheimer’s Disease Risk Index and explained variance-weighted genetic risk scores and cognitive impairment at waves 1–4

ANU-ADRI^a, HR (95% CI)

1.06 (1.03–1.09)^b

1.04 (1.02–1.50)^b

EV-GRS^c, HR (95% CI)

1.14 (0.98–1.33)

1.04 (0.96–1.12)

C-index (SE)

0.61 (0.03)

0.56 (0.01)

 ANU-ADRI

0.60 (0.05)

0.56 (0.02)

 EV-GRS

0.53 (0.05)

0.51 (0.02)