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Table 1 Participant demographics

From: Retinal vascular and structural changes are associated with amyloid burden in the elderly: ophthalmic biomarkers of preclinical Alzheimer’s disease

 

Elderly control group (NAL <1.4)

Preclinical AD group (NAL ≥1.4)

Clinical AD cohort

Number of participants

50

23

28

Males/females

14/36

9/14

16/12

Mean age, years

79 ± 5

80 ± 4

70 ± 9

Mean IOP, mmHg

14 ± 3

13 ± 3

13 ± 3

Mean SBP, mmHg

153 ± 14

142 ± 18

137 ± 17

Mean DBP, mmHg

83 ± 15

77 ± 18

80 ± 8

Mean Aβ, SUVR

1.17 ± 0.09

1.75 ± 0.24

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  1. Abbreviations: Aβ Amyloid-β, AD Alzheimer’s disease, DBP Diastolic blood pressure, IOP Intra-ocular pressure, NAL Neocortical amyloid load, SBP Systolic blood pressure, SUVR Standardised uptake value ratio
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Alzheimer's Research & Therapy

ISSN: 1758-9193