| | |
Event
|
PYs
|
Adjusted model
|
|---|
| | |
HR
|
95% CI
|
p valuea
|
|---|
|
Adjusted confounders without heart related diseases and stroke
|
|
DM cohort
|
Both HTN and HPLb
|
126
|
24,637
|
0.90
|
0.65–1.24
|
0.514
|
|
HTN onlyb
|
124
|
11,533
|
1.16
|
0.85–1.59
|
0.359
|
|
HPL onlyb
|
25
|
13,785
|
0.71
|
0.44–1.15
|
0.161
|
|
No HTN and HPL
|
58
|
12,932
|
1.00
| | |
|
Non-DM cohort
|
Both HTN and HPLb
|
130
|
24,367
|
1.35
|
1.10–1.66
|
0.004
|
|
HTN onlyb
|
418
|
59,711
|
1.23
|
1.07–1.42
|
0.004
|
|
HPL onlyb
|
31
|
12,468
|
1.29
|
0.90–1.87
|
0.170
|
|
No HTN and HPL
|
402
|
217,378
|
1.00
| | |
|
Age between 40 and 80 years (n = 43,320)
|
|
DM cohort
|
Both HTN and HPLc
|
119
|
22,358
|
0.86
|
0.61–1.22
|
0.396
|
|
HTN onlyc
|
112
|
10,409
|
1.12
|
0.80–1.58
|
0.513
|
|
HPL onlyc
|
25
|
10,657
|
0.75
|
0.46–1.23
|
0.255
|
|
No HTN and HPL
|
48
|
8709
|
1.00
| | |
|
Non-DM cohort
|
Both HTN and HPLc
|
127
|
23,444
|
1.33
|
1.07–1.64
|
0.009
|
|
HTN onlyc
|
356
|
55,729
|
1.23
|
1.06–1.44
|
0.008
|
|
HPL onlyc
|
28
|
11,257
|
1.19
|
0.81–1.75
|
0.380
|
|
No HTN and HPL
|
354
|
166,275
|
1.00
| | |
-
CI confidence interval, COPD chronic obstructive pulmonary disease, DM diabetes mellitus, HTN hypertension, HPL hyperlipidemia, HR hazard ratio, PYs person-years
-
aTested using Cox proportional hazards regression
-
bAdjusted for age, sex, kidney disease, depression, anxiety, alcoholism, chronic obstructive pulmonary disease, obesity, and insurance amount
-
cAdjusted for age, sex, coronary heart disease, stroke, kidney disease, atrial fibrillation, depression, anxiety, heart failure, alcoholism, chronic obstructive pulmonary disease, obesity, and insurance amount
