Skip to main content

Table 3 Number of subjects of subsample between 2001 and 2007 according to diagnosis at baseline, outcome at follow-up, and cerebrospinal fluid β-amyloid 1–42 cutoff score

From: Unbiased estimates of cerebrospinal fluid β-amyloid 1–42 cutoffs in a large memory clinic population

  Total group (n = 688) CSF Aβ42 cutoff <550 pg/ml CSF Aβ 42 cutoff <615 pg/ml
AD-type dementia, n (%) 288 (42) 236 (82) 255 (89)
Non-AD-type dementia, n (%) 143 (21) 49 (34) 55 (38)
SCD with follow-up available
 Converted to AD-type dementia, n (%) 7 (7) 5 (71) 6 (86)
 Not converted to AD-type dementia, n (%) 91 (93) 16 (18) 20 (22)
MCI with follow-up available
 Converted to AD-type dementia, n (%) 69 (53) 53 (77) 60 (87)
 Not converted to AD-type dementia, n (%) 60 (47) 16 (27) 26 (43)
  1. Data are from the subsample of patients seen between 2001 and 2007. For this time period, the cutoff for CSF Aβ 42 determined with Gaussian mixture modeling was 615 pg/ml
  2. Abbreviations: CSF Cerebrospinal fluid, 42 Amyloid-β 1–42, SCD Subjective cognitive decline, MCI Mild cognitive impairment, AD Alzheimer’s disease