From: Unbiased estimates of cerebrospinal fluid β-amyloid 1–42 cutoffs in a large memory clinic population
Log-likelihood 1 versus 2 components | Log-likelihood 2 versus 3 components | |||||
---|---|---|---|---|---|---|
Observed | Bootstrap (95% CI) | p Value | Observed | Bootstrap (95% CI) | p Value | |
All subjects | 653.98 | 6.51 (1.65–15.69) | <0.001 | 2.16 | 16.67 (0.78–11.15) | 0.77 |
Subjective cognitive decline | 15.64 | 6.12 (1.72–13.25) | 0.03 | 2.45 | 5.8 (0.94–17) | 0.74 |
Mild cognitive impairment | 124.50 | 5.79 (1.91–12.63) | <0.001 | 9.95 | 5.55 (0.54–10.82) | 0.08 |
Nondemented | 132.93 | 6.44 (1.5–13.1) | <0.001 | 10.41 | 4.34 (0.73–11.3) | 0.07 |
Dementia | 471.81 | 6.01 (1.49–13.21) | <0.001 | 3.61 | 4.34 (0.53–9.56) | 0.55 |
Younger than 66.5 years old | 261.16 | 5.86 (1.4–12.82) | <0.001 | 2.02 | 4.64 (0.65–9.83) | 0.79 |
Older than 66.5 years old | 397.49 | 6.42 (1.82–14.46) | <0.001 | 9.39 | 4.82 (0.68–11.64) | 0.11 |
APOE ε4 noncarrier | 138.75 | 6 (1.77–13.01) | <0.001 | 4.19 | 6.91 (0.79–11.26) | 0.41 |
APOE ε4 carrier | 367.29 | 5.83 (1.89–11.50) | <0.001 | 10.49 | 7.25 (0.6–11.79) | 0.07 |