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Table 3 Correlations between regional glucose metabolism, gray matter volume and plasma apoE concentrations

From: Peripheral apoE isoform levels in cognitively normal APOE ε3/ε4 individuals are associated with regional gray matter volume and cerebral glucose metabolism

apoE4/E3 ratio negative association Brain region Coordinates (X, Y, Z) p value
CMRgl Hippocampus_R 26, –12, –12 2.49 × 10–4 a
GMV Cingulate_Post 4, –40, 21 5.60 × 10–4 b
  Hippocampus_L –16, –34, 9 4.91 × 10–3
  Lateral Temporal_L –48, –64, –3 2.81 × 10–3
  Lateral Temporal_R 60, –31, 13 1.83 × 10–4
  Medial Temporal_L –16, –34, 9 4.91 × 10–3
  Precuneus_R 8, –43, 18 1.87 × 10–3
  1. a Survived correction at a 0.05 level
  2. b Survived correction at a 0.059 level
  3. CMRgl cerebral metabolic rate of glucose, GMV gray matter volume