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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: An update on semantic dementia: genetics, imaging, and pathology

Fig. 2

Brain imaging findings in SD at presentation and with disease progression. a Cross-sectional multimodal imaging findings in 10 SD patients versus 21 healthy controls: reduced regional grey matter density (top row), reduced FDG-PET (second row), increased radial diffusivity (third row), and composite of multimodal findings (fourth row). From Acosta-Carbonero et al. [31] with permission. b Baseline and longitudinal changes in cortical thickness in 22 left SD vs 9 right SD patients. From Kumfor et al. [14, 38] with permission. c Longitudinal white matter changes from baseline in 11 SD patients. From Lam et al. [40] with permission. FA fractional anisotropy, FDG-PET fluorodeoxyglucose positron emission tomography, FDR, L left, MD mean diffusivity, R right, RadialD radial diffusivity, SD semantic dementia, TBSS tract-based spatial statistics, VBM voxel-based morphometry, FDR false discovery rate

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