Outcomes measures in a decade of dementia and mild cognitive impairment trials

Table 3 Use of other outcome measures across included records

	Quality of life		Mood		Behaviour		Global
Number of records reported^a	102 (13 %)		174 (22 %)		303 (38 %)		247 (31 %)
Total number of assessments^b	118		207		365		279
Number of unique assessments^c	21		41		32		25
	Assessment tool	n	Assessment tool	n	Assessment tool	n	Assessment tool	n
	1. Quality of Life in Alzheimer’s Disease	36	1. Geriatric Depression Scale	47	1. Neuropsychiatric Inventory	183	1. Clinician’s Interview-Based Impression of Change plus caregiver interview	41
	2. No tool	27	2. Cornell Scale for Depression in Dementia	41	2. Cohen-Mansfield Agitation Inventory	53	2. Clinical Dementia Rating – Sum of Boxes	30
	3. EQ-5D	15	3. Brief Psychiatric Rating Scale	13	3. No tool	37	3. Clinical Global Impression	29
	4. DEMQOL/DEMQOL proxy	10	3. Hamilton Rating Scale for Depression	13	4. Neuropsychiatric Inventory – Nursing Home	16	4. Clinical Dementia Rating	28
	5. QUALID and QUALIDEM	4	5. No tool	12	4. BEHAVE-AD	16	5. Clinical Global Impression of Change	27

Abbreviations: EQ-5D EuroQol questionnaire, DEMQOL Dementia Quality of Life measure, QUALID Quality of life in late-stage dementia, QUALIDEM a dementia specific quality of life questionnaire rated by professionals, BEHAVE-AD Behavioral Pathology in Alzheimer’s Disease
^aNumber of records in ALOIS where a measure was reported at least one
^bTotal number of times an outcome measure is used in all included records
^cTotal number of unique assessment measures used at least once

ISSN: 1758-9193