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Table 4 Statistical analysis of association between normal control and aMCI ethnic cohorts

From: Identifying biomarkers of dementia prevalent among amnestic mild cognitively impaired ethnic female patients

Biomarker

Ethnicity

p value, NC vs aMCI

Aβ40

White

0.0001***

African American

0.4480

Hispanic

0.0110*

Aβ42

White

0.7650

African American

0.5100

Hispanic

0.0020**

Aβ42/Aβ40

White

0.0800*

African American

0.6570

Hispanic

0.5240

Total tau

White

0.3700

African American

0.0460*

Hispanic

0.7070

Cystatin C

White

0.0970

African American

0.0630

Hispanic

0.0460*

YKL40

White

0.4180

African American

0.9880

Hispanic

0.0330*

  1. Indicated are the levels of biochemically measured plasma biomarkers that displayed significant changes controlled for ethnicity and compared with NC cohort. Statistical analyses were performed in a two by three factorial design with post-hoc analyses using IBM SPSS Statistics 22. An outlier test was also performed using IBM SPSS Statistics 22. Significant changes in biomarkers related to ethnic background: *p < 0.05, **p < 0.01 ***p < 0.001
  2. aMCI amnestic mild cognitive impairment, NC age-matched control group
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Alzheimer's Research & Therapy

ISSN: 1758-9193