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Table 1 Baseline characteristics of participants with persistent MPS and controls

From: Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs

 

Controls (n = 428)

Persistent MPS (n = 52)

p value

Male gender (N (%))

182 (43)

34 (65)

0.002

Age (years)

62 (50–80)

67 (51–77)

<0.001

(62 ± 7)

(67 ± 6)

Education (years)

14 (9–21)

13 (9–21)

0.030

(15 ± 3)

(14 ± 3)

Family history PD (%)

63 (15)

8 (15)

0.838

Family history dementia (%)

167 (39)

12 (23)

0.033

MMSE (0–30)

29 (25–30)

29 (25–30)

0.173

(29 ± 1)

(28 ± 1)

MDS-UPDRS-III (0–132)

0 (0–10)

4 (2–17)

<0.001

(1 ± 2)

(5 ± 3)

Lifetime depression (%)

155 (36)

20 (39)

0.762

Hyposmia (%)

95 (22)

15 (29)

0.216

RBD (%)

81 (19)

18 (35)

0.011

BDI-I (0–63)

6 (0–38)

6 (0–38)

0.121

(7 ± 6)

(9 ± 7)

Hyperechogenic substantia nigra (%)

106 (25)

19 (37)

0.075

ApoE4 positive (%)

94 (22)

12 (23)

0.931

  1. Data are presented as median (range) (mean ± standard deviation) or number (percentage of total)
  2. ApoE4 apolipoprotein 4, BDI-I Beck Depression Inventory I, MMSE Mini Mental State Examination, MPS mild parkinsonian signs, PD Parkinson’s disease, RBD rapid eye movement sleep behaviour disorder, MDS-UPDRS-III Unified Parkinson’s Disease Rating Scale part 3