From: Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs
Controls (n = 428) | Persistent MPS (n = 52) | p value | |
---|---|---|---|
Male gender (N (%)) | 182 (43) | 34 (65) | 0.002 |
Age (years) | 62 (50–80) | 67 (51–77) | <0.001 |
(62 ± 7) | (67 ± 6) | ||
Education (years) | 14 (9–21) | 13 (9–21) | 0.030 |
(15 ± 3) | (14 ± 3) | ||
Family history PD (%) | 63 (15) | 8 (15) | 0.838 |
Family history dementia (%) | 167 (39) | 12 (23) | 0.033 |
MMSE (0–30) | 29 (25–30) | 29 (25–30) | 0.173 |
(29 ± 1) | (28 ± 1) | ||
MDS-UPDRS-III (0–132) | 0 (0–10) | 4 (2–17) | <0.001 |
(1 ± 2) | (5 ± 3) | ||
Lifetime depression (%) | 155 (36) | 20 (39) | 0.762 |
Hyposmia (%) | 95 (22) | 15 (29) | 0.216 |
RBD (%) | 81 (19) | 18 (35) | 0.011 |
BDI-I (0–63) | 6 (0–38) | 6 (0–38) | 0.121 |
(7 ± 6) | (9 ± 7) | ||
Hyperechogenic substantia nigra (%) | 106 (25) | 19 (37) | 0.075 |
ApoE4 positive (%) | 94 (22) | 12 (23) | 0.931 |