Fig. 2
From: The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer’s disease
ROC curve analysis of synaptotagmin in human CSF. ROC curve analysis for synaptotagmin 215–223 (green and pink) and synaptotagmin 238–245 (turquoise and black) in CSF for differentiation of MCI due to Alzheimer’s disease (MCI-AD) from controls in sample set I and sample set II, respectively (a). ROC curve analysis for synaptotagmin 215–223 (green and pink) and synaptotagmin 238–245 (turquoise and black) in CSF for differentiation of dementia due to Alzheimer’s disease (AD) from controls in sample set I and sample set II, respectively (b). The area under the curve (95 % confidence interval) is shown in the included table (c). AD dementia due to Alzheimer’s disease, MCI-AD mild cognitive impairment due to Alzheimer’s disease (Color figure online)