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Table 1 Summary of group demographics and neuropsychological assessment of cognitive domains

From: Regional tau deposition measured by [18F]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer’s disease

  MCI PiB-positive (prodromal AD) AD dementia
Number 11 9
Demographics
 Age at testing (years) 69.7 ± 6.7 67.3 ± 7.1
 Education 12.5 ± 3.3 13.3 ± 2.7
 Gender (M/F) 5/6 2/7
 ApoE ε3ε3/ε3ε4/ε4ε4 4/1/5 1/5/3
Cognitive functions
Global cognition
 MMSE 27.7 ± 3.0 22.6 ± 3.3**
 FSIQ 92.6 ± 12.2 69.2 ± 21.6*
 (z-scores) −0.8 ± 0.9 −2.6 ± 1.6
Episodic memory
 RAVL, learning 34.7 ± 10.0 20.9 ± 5.7**
 (z-scores) −1.2 ± 1.0 −2.5 ± 0.5
 RAVL, delayed recall 3.8 ± 3.0 1.7 ± 2.2
 (z-scores) −1.8 ± 0.9 −2.4 ± 0.6
 Rey, delayed recall 12.8 ± 8.1 1.2 ± 1.9**
 (z-scores) −1.0 ± 1.2 −2.7 ± 0.3
  1. Performance is expressed as mean ± standard deviation to the mean. Z-scores were calculated in comparison to a normative population
  2. Statistically significant differences between groups are displayed as *p < 0.05; **p < 0.01
  3. AD Alzheimer’s disease, ApoE apolipoprotein E, F female, FSIQ full-scale intelligence quotient, M male, MCI mild cognitive impairment, MMSE mini mental state examination, PiB Pittsburgh Compound B, RAVL Rey auditory verbal learning test, Rey Rey-Osterrieth complex figure test