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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

Fig. 3

FRM-36143 affects multiple Aβ isoforms to different extents. Mass spectrometry traces showing the peptide profile in H4 cell culture media after overnight treatment with DMSO (left) or 300 nM FRM-36143 (right). Measurements are semi-quantitative. Note that peak height is relative for each Aβ isoform, and it should not be compared between peptides since the ionization efficiency and hydrophobicity might be different for each Aβ isoform

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Alzheimer's Research & Therapy

ISSN: 1758-9193