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Table 1 Characteristics of the study population before cerebrospinal fluid biomarker diagnosis

From: Utility of CSF biomarkers in psychiatric disorders: a national multicentre prospective study

  Study population BNA population BNA/study population comparison
  Overall Psychiatric disorder p Value Overall Psychiatric disorder p value p Value
Number of patients 1015 69 (6.79)   317,515 24,561 (7.74)   0.29
Age, years, mean (SD) 69.2 (10.03) 64.57 (11.57) 0.0018 76.86 (12.18) 71.43 (13.82) <0.0001 <0.0001
Female sex, n (%) 504 (49.7) 43 (61.4) 0.056 199,085 (62.7) 17,661 (71.91) <0.0001 0.46
Final diagnosis of AD, n (%) 395 (38.9) 13 (18.8) 0.009 70,651 (22.25) 536 (2.18) <0.0001 <0.0001
Changed diagnosis, n (%) 231 (24.1) 19 (27.5) 0.62   1821 (7.41)   <0.0001
Improvement in diagnosis confidence level, % 19.6 25.2 0.027     
Changed treatment, n (%) 437 (43.1) 24 (34.8) 0.13     
  1. AD Alzheimer’s disease, BNA Banque Nationale Alzheimer