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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Classification of the primary progressive aphasias: principles and review of progress since 2011

Fig. 3

Metabolic patterns. a Typical SV PET pattern. b, c Two PPA cases with a combination of left anterior temporal hypometabolism together with posterior inferior temporal and inferior parietal hypometabolism. This could pose diagnostic problems as there are features of both AD and SV. In the right hemisphere, however, the hypometabolism is more pronounced in posterior than in anterior temporal cortex, suggesting that the damage progressed in the left hemisphere from posterior to anterior temporal cortex. In both cases cerebrospinal fluid AD biomarkers were clearly within the typical AD range (Aβ42 = 393 pg/ml and total tau = 458 pg/ml in b; Aβ42 = 525 pg/ml and total tau >1200 in c)

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