Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease

Table 2 Correlation analyses of CSF sTREM2 in relation to age in the Norwegian and the Swedish cohorts

	Correlations between sTREM2 and age
	Norwegian cohort					Swedish cohort			Norwegian and Swedish cohort
	All (n = 100)	AD (n = 29)	MCI (n = 21)	Control (n = 50)	Aβ42 > 700 (n = 46)	All (n = 50)	AD (n = 25)	Control (n = 25)	All (n = 150)	AD (n = 54)	Control (n = 75)
Age	r = 0.34	r = 0.08	r = 0.03	r = 0.53	r = 0.56	r = 0.35	r = 0.46	r = 0.35	r = 0.29	r = 0.00	r = 0.50
Age	p < 0.001	p = 0.69	p = 0.86	p < 0.001	p < 0.001	p = 0.01	p = 0.02	p = 0.08	p < 0.001	p = 1.00	p < 0.001

Correlation analyses of CSF sTREM2 in relation to age of AD, MCI and control patients of the two cohorts
Correlations are presented as Spearman rho (r) since most data not were normally distributed
Aβ42 amyloid beta 1–42, AD Alzheimer’s disease, CSF cerebrospinal fluid, MCI mild cognitive impairment, sTREM2 soluble triggering receptor expressed on myeloid cells 2

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