Fig. 4From: A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humansTransmembrane location of Aβ22-28 and APLP1β17. Location of the peptides (a) Aβ22-28 and (b) APLP1β17 relative to the transmembrane region of their respective protein sequences. The γ-secretase cleavage sites in APP are indicated with arrows. APP amyloid precursor proteinBack to article page