Skip to main content

Table 7 One-sample paired t-test for change from baseline to week 32 of cerebrospinal fluid biomarkers in the 8 mg/kg group

From: First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer’s disease

Biomarker

Mean change

80 % CI

95 % CI

P value

Aβx-40 (pg/ml)

113.53

(–170.30, 397.35)

(–339.06, 566.12)

0.599

Aβx-42 (pg/ml)

48.85

(–11.79, 109.48)

(–47.84, 145.53)

0.297

Tau (pg/ml)

−15.26

(–53.54, 23.02)

(–76.30, 45.78)

0.600

P-tau (pg/ml)

1.23

(–1.89, 4.35)

(–3.74, 6.21)

0.603

  1. CI Confidence interval
Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193