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Table 2 ADAS-Cog 11 scores at each visit and change from baseline for MCI patients

From: Alzheimer’s Disease Assessment Scale–Cognitive subscale variants in mild cognitive impairment and mild Alzheimer’s disease: change over time and the effect of enrichment strategies

  MCI (non-enriched) MCI+ (enriched) MCI− (‘biomarker-negative’)
  Number of subjects ADAS-Cog 11 CFB Number of subjects ADAS-Cog 11 CFB Number of subjects ADAS-Cog 11 CFB
Baseline/screen 382 9.5 ± 4.29   206 10.83 ± 4.46   176 7.94 ± 3.49  
Month 6 376 9.6 ± 4.75 0.0 ± 3.40 204 11.16 ± 4.82 0.3 ± 3.61 172 7.70 ± 3.91 −0.31 ± 3.10
Month 12 380 9.3 ± 5.23 −0.2 ± 3.68 206 11.08 ± 5.54 0.3 ± 4.06 174 7.27 ± 3.95 −0.68 ± 3.10
Month 24 382 10.4 ± 6.40 0.9 ± 4.45 206 12.74 ± 6.87 1.9 ± 4.92 176 7.70 ± 4.48 −0.24 ± 3.51
Month 36 169 10.8 ± 7.06 1.9 ± 5.45 89 13.83 ± 7.86 3.7 ± 6.21 80 7.40 ± 3.90 −0.26 ± 3.41
  1. ADAS-Cog Alzheimer’s Disease Assessment Scale–Cognitive subscale, CFB change from baseline, MCI mild cognitive impairment
  2. Increased score on ADAS-Cog 11 (maximum total score 70) indicates cognitive worsening. Data are presented as mean ± SD