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Table 4 Attention test (visual sustained attention)

From: Cognitive impact after short-term exposure to different proton pump inhibitors: assessment using CANTAB software

Rapid Visual Information Processing (RVP)
Drug Name of task Mean ± SEM p1 value 95 % CI-D (Lower, Upper) Cohen’s d for p1 Value p2 Value 95 % CI-D (Lower, Upper) Cohen’s d for p2 Value
Baseline After 7 Days
OME RVP A' 0.940 ± 0.014 0.920 ± 0.015 0.030* −0.001, 0.050 1.428ǂ 0.492 −0.045, 0.044 0.009 (S)
LAN RVP A' 0.920 ± 0.013 0.900 ± 0.009 0.043* −0.004, 0.044 1.281ǂ 0.251 −0.049, 0.025 0.322 (S)
RAB RVP A' 0.934 ± 0.013 0.900 ± 0.016 0.037* −0.004, 0.072 1.343ǂ 0.248 −0.062, 0.031 0.327 (S)
PAN RVP A' 0.931 ± 0.010 0.900 ± 0.016 0.029* −0.001, 0.063 1.445ǂ 0.248 −0.063, 0.031 0.328 (S)
ESO RVP A' 0.940 ± 0.016 0.918 ± 0.010 0.032* −0.002, 0.046 1.398ǂ 0.441 −0.035, 0.040 0.071 (S)
CON RVP A' 0.901 ± 0.013 0.915 ± 0.015 0.217 −0.054, 0.025 N/A
  1. Values are expressed as mean ± SEM (n=10), 95 % CI-D=95 % Confidence Interval of the Difference (lower, upper), p1= p value found after Paired-Samples t-test within volunteers (five test groups) before and after consuming drugs and placebo (one control group) respectively with degree of freedom (df)=9; p2= p value found after Independent-Samples t-test between each five test groups with control group having degree of freedom (df)=18 . * indicates statistically significant at alpha (<0.05). ǂ indicates large effect size in Cohen’s d value