|
Motor Screening Test (MOT)
|
|---|
|
Drug
|
Name of task
|
Mean ± SEM
|
p1 value
|
95 % CI-D (Lower, Upper)
|
Cohen’s d for p1 Value
|
p2 Value
|
95 % CI-D (Lower, Upper)
|
Cohen’s d for p2 Value
|
|---|
|
Baseline
|
After 7 Days
|
|---|
|
OME
|
MOT M latency
|
784.300 ± 48.095
|
849.200 ± 80.201
|
0.206
|
−235.741, 105.941
|
0.573
|
0.292
|
−143.601, 244.661
|
0.305
|
|
MOT M error
|
7.400 ± 0.427
|
9.600 ± 1.166
|
0.038*
|
−4.696, 0.296
|
1.329ǂ
|
0.187
|
−1.577, 3.997
|
0.429
|
|
LAN
|
MOT M latency
|
744.400 ± 24.413
|
865.700 ± 58.618
|
0.014*
|
−226.980, -15.620
|
1.731ǂ
|
0.181
|
−83.723, 217.563
|
0.439
|
|
MOT M error
|
8.600 ± 0.686
|
9.600 ± 0.968
|
0.171
|
−3.262, 1.262
|
0.667
|
0.101
|
−0.885, 3.813
|
0.702
|
|
RAB
|
MOT M latency
|
890.000 ± 53.938
|
883.900 ± 48.187
|
0.470
|
−171.647, 184.847
|
0.051
|
0.098
|
−48.222, 218.502
|
0.632
|
|
MOT M error
|
7.000 ± 0.615
|
8.500 ± 1.276
|
0.166
|
−4.808, 1.808
|
0.684
|
0.451
|
−2.849, 3.198
|
0.071
|
|
PAN
|
MOT M latency
|
768.100 ± 40.731
|
847.900 ± 36.554
|
0.009**
|
−143.281, -16.319
|
1.896ǂ
|
0.191
|
−66.545, 165.045
|
0.421
|
|
MOT M error
|
9.700 ± 0.870
|
9.900 ± 0.767
|
0.405
|
−2.041, 1.641
|
0.164
|
0.045*
|
−0.283, 3.537
|
0.843ǂ
|
|
ESO
|
MOT M latency
|
696.300 ± 52.443
|
788.700 ± 60.783
|
0.096
|
−241.107, 56.307
|
0.937ǂ
|
0.446
|
−164.470,144.343
|
0.065
|
|
MOT M error
|
9.100 ± 0.722
|
10.300 ± 0.597
|
0.044*
|
−2.623, 0.223
|
1.272ǂ
|
0.010**
|
0.352, 3.748
|
1.196ǂ
|
|
CON
|
MOT M latency
|
853.700±53.702
|
798.700 ± 41.260
|
0.088
|
−29.868, 139.868
|
N/A
|
|
MOT M error
|
9.500 ± 0.687
|
8.300 ± 0.539
|
0.073
|
−0.513, 2.913
|
N/A
|
- Values are expressed as mean ± SEM (n=10), M=Mean, 95 % CI-D=95 % Confidence Interval of the Difference (lower, upper), p1= p value found after Paired-Samples t-test within volunteers (five test groups) before and after consuming drugs and placebo (one control group) respectively with degree of freedom (df)=9; p2 = p value found after Independent-Samples t-test between each five test groups with control group having degree of freedom (df)=18. * and ** indicate statistically significant at alpha (<0.05) & (<0.01) respectively. ǂ indicates large effect size in Cohen’s d value
