Table 3 Demographic and cognitive characteristics of the SPECT subjects sample, disaggregated for increased levels of alpha3/alpha2
Demographic and clinical features | At low-risk | At high-risk | p |
|---|---|---|---|
MCI | MCI | ||
Number | 14 | 13 | |
Age (years) [Range] | 69.1 ± 7.6 [57÷83] | 70.6 ± 5.5 [62÷78] | 0.555 |
Gender (females) | 6 (43 %) | 9 (69 %) | 0.168 |
Education (years) [Range] | 8.2 ± 4.3 [4÷18] | 7.9 ± 4.5 [3÷18] | 0.865 |
MMSE score [Range] | 27.9 ± 1.6 [25÷30] | 27.2 ± 1.9 [24÷29] | 0.309 |
ApoE ε4 genotype (carriers) | 2 (29 %) | 5 (39 %) | 0.152 |
Left hippocampal volume (mm3) [Range] | 2,606 ± 353 [1,923÷3,017] | 2,073 ± 412 [1,234÷2,641] | 0.001 |
Right hippocampal volume (mm3) [Range] | 2,581 ± 473 [1,549÷3,150] | 2,296 ± 501 [1,589÷3,086] | 141 |
Wahlund total score [Range] | 3.58 ± 3.29 [0.0÷10.0] | 3.78 ± 2.63 [0.0÷7.0] | 0.886 |