Fig. 2

Neurogranin is correlated with total tau (t-tau), phosphorylated tau (p-tau), and β-amyloid (Aβ₄₀), especially in subjects without Alzheimer’s disease (non-AD). Cerebrospinal fluid levels of neurogranin in the non-AD group (a, c, e, g, and i) and patients in the AD group (b, d, f, h, and j) are plotted against YKL-40 (a, b) and core AD biomarkers (c–j). Correlations were calculated using Spearman’s rank correlation coefficient