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Table 2 Tandem mass spectrometric identification of APLP1 peptides

From: APLP1 as a cerebrospinal fluid biomarker for γ-secretase modulator treatment

Peptide Observed m/z ppm Ion score Expect a/b/y ions
APLP1β14 1372.71 30.4 48 1.6x10-5 –/4/6
APLP1β17 1615.83 23.7 79 1.3x10-8 4/6/11
APLP1β18 1728.91 21.9 65 3.0x10-7 –/8/10
APLP1β19 1842.06 56.7 18 1.7x10-2 –/5/4
APLP1β21 2086.19 48.1 24 3.9x10-3 –/6/–
APLP1β23 2214.14 −2.91 15 3.3x10-2 –/4/–
APLP1β25 2328.51 138 79 1.3x10-8 7/6/11
APLP1β27 2472.31 27.8 100 9.4x10-11 9/5/9
APLP1β28 2585.40 28.3 93 5.3x10-10 9/11/10
  1. The Table shows the peptides that were identified by tandem mass spectrometry. The acquired fragment mass spectra were used for searching an in-house Mascot Deamon server containing a designated amyloid-like protein 1 (APLP1) database. Also shown are the observed masses and the deviation from the theoretical masses in ppm, as well as identification statistics given as the Mascot Ion Score and Expect value. The number of identified a, b and y ions are also indicated