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Table 2 Mean values of AD CSF biomarkers, gravity versus aspiration

From: Alzheimer’s disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology

  N Aβ42 [pg/mL] t-tau [pg/mL] p-tau [pg/mL]
g a p-value g a p-value g a p-value
Complete 44 366.5 (86.8) 354.3 (82.6) 0.10 83.9 (46.6) 84.7 (47.4) 0.49 43.5 (22.8) 40.0 (17.7) 0.05
HC 31 394.6 (56.4) 381.6 (65.8)   68.6 (27.9) 68.2 (28.8) 0.57 35.3 (12.1) 33.4 (11.5)  
MCI 6 344.2 (73.5) 346.8 (55.7)   118.6 (65.1) 122.5 (68.6) 0.31 62.1 (28.9) 51.7 (18.4)  
AD 7 261.38 (126.9) 240.04 (73.9)   121.92 (63.8) 125.27 (57.4) 0.58 63.86 (33.3) 59.08 (23.3)  
  1. Mean (standard deviation)
  2. g gravity fed; a aspiration, t-tau total tau, p-tau phosphorylated-tau
  3. p-values are unadjusted from Paired Sample T-tests
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Alzheimer's Research & Therapy

ISSN: 1758-9193