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Table 1 Sub-cohort demographics

From: Alzheimer’s disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology

 

HC

MCI

AD

p - value

N

31

6

7

 

Age (years)

71.8 (5.6)

68.3 (4.5)

71.3 (7.1)

0.40

Sex (F%)

58 %

50 %

28 %

0.41

APOEε4 %

19 %

0 %

43 %

0.20

MMSE (median IQR)

29 (1.5)

26 (2)

22 (3)

<0.0001

CDR (median IQR)

0 (0)

0.5 (0)

1 (0.25)

<0.0001

  1. p–value determined by t-test (age), Chi square analyses (APOEε4 and sex) and Kruskal-Wallis tests (CDR score and MMSE)
  2. N number, HC health control, MCI mild cognitive impairment, AD Alzheimer’s disease, APOEε4 apolipoprotein epsilon 4 allele, MMSE Mini–Mental State Examination, CDR Clinical Dementia Rating, IQR inter-quartile range