Skip to main content

Table 1 Demographic data and neuroimaging characteristics of the subjects

From: Hippocampal atrophy but not white-matter changes predicts the long-term cognitive response to cholinesterase inhibitors in Alzheimer’s disease

Baseline characteristics

Mean ± SD, or number (%)

Age of starting ChEI (year)

74.1 ± 10.3

Gender, female/male, No. (%)

218/135 (62/38)

Education (year)

8.9 ± 5.1

Baseline TMSE

19.7 ± 4.1

Baseline CDR, No. (%)

 

 0.5

195 (55)

 1

129 (36)

 2 ~ 3

19 (5)

Total MTA score

3.4 ± 1.7

Maximum MTA score, No. (%)

 

 0

23 (7)

 1

86 (24)

 2

174 (49)

 3

61 (17)

 4

9 (3)

Prominent MTA adjusted by age, No. (%)

136 (39)

Total WMH score

3.6 ± 3.1

Total WMH score, No. (%)

 

 0 ~ 3

165 (47)

 4 ~ 7

125 (35)

 8 ~ 12

64 (18)

Number of areas with WMH score > =2

 

 0

237 (67)

 1 ~ 2

49 (14)

 3 ~ 4

67 (19)

  1. CDR Clinical Dementia Rating, ChEI cholinesterase inhibitor, MTA medial temporal atrophy, TMSE Taiwanese Mini-Mental State Examination, WMH white matter hyperintensity