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Table 1 Demographic data and neuroimaging characteristics of the subjects

From: Hippocampal atrophy but not white-matter changes predicts the long-term cognitive response to cholinesterase inhibitors in Alzheimer’s disease

Baseline characteristics Mean ± SD, or number (%)
Age of starting ChEI (year) 74.1 ± 10.3
Gender, female/male, No. (%) 218/135 (62/38)
Education (year) 8.9 ± 5.1
Baseline TMSE 19.7 ± 4.1
Baseline CDR, No. (%)  
 0.5 195 (55)
 1 129 (36)
 2 ~ 3 19 (5)
Total MTA score 3.4 ± 1.7
Maximum MTA score, No. (%)  
 0 23 (7)
 1 86 (24)
 2 174 (49)
 3 61 (17)
 4 9 (3)
Prominent MTA adjusted by age, No. (%) 136 (39)
Total WMH score 3.6 ± 3.1
Total WMH score, No. (%)  
 0 ~ 3 165 (47)
 4 ~ 7 125 (35)
 8 ~ 12 64 (18)
Number of areas with WMH score > =2  
 0 237 (67)
 1 ~ 2 49 (14)
 3 ~ 4 67 (19)
  1. CDR Clinical Dementia Rating, ChEI cholinesterase inhibitor, MTA medial temporal atrophy, TMSE Taiwanese Mini-Mental State Examination, WMH white matter hyperintensity