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Table 4 Characteristics (mean (SD)) of participants above and below selected cutoffs

From: Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers

< −1.0 SD on two memory tests Below cutoff Above cutoff F P
(n = 196) (n = 291)
Category fluency, z score −0.40 (1.11) 0.38 (1.28) 14.23 <0.001
BNT, scaled score 10.09 (3.62) 12.55 (3.56) 25.60 <0.001
Trails B/A ratio, z score 0.01 (1.14) −0.45 (0.82) 7.18 <0.001
BPF 0.81 (0.03) 0.82 (0.03) 49.02 <0.001
Left HP volume, cm3 0.23 (0.03) 0.27 (0.03) 44.83 <0.001
Right HP volume, cm3 0.25 (0.03) 0.28 (0.03) 41.03 <0.001
v CSF, cm3 3.52 (1.59) 3.19 (1.49) 28.99 <0.001
WMH, cm3 0.63 (1.34) 0.87 (2.70) 8.69 <0.0001
< −1.5 SD on one memory test Below cutoff Above cutoff F P
(n = 264) (n = 223)
Category fluency, z score −0.31 (1.11) 0.51 (1.31) 14.23 <0.001
BNT, scaled score 10.47 (3.71) 12.85 (3.45) 24.00 <0.001
Trails B/A ratio, z score −0.11 (1.08) −0.45 (0.83) 3.81 0.005
BPF 0.81 (0.03) 0.82 (0.02) 44.99 <0.001
Left HPV, cm3 0.24 (0.03) 0.27 (0.03) 27.38 <0.001
Right HPV (cm3) 0.25 (0.03) 0.29 (0.03) 33.42 <0.001
v CSF, cm3 3.53 (1.63) 3.07 (1.40) 28.94 <0.001
WMH, cm3 0.82 (2.31) 0.72 (2.19) 8.89 <0.001
< −2.0 SD on one memory test Below cutoff Above cutoff F P
(n = 174) (n = 313)
Category fluency, z score −0.42 (1.05) 0.33 (1.31) 11.61 <0.001
BNT, scaled score 10.19 (3.71) 12.32 (3.60) 19.22 <0.001
Trails B/A ratio, z score −0.08 (1.12) −0.37 (0.89) 3.40 0.009
BPF 0.81 (0.03) 0.82 (0.03) 45.07 <0.001
Left HPV, cm3 0.23 (0.03) 0.26 (0.03) 31.79 <0.001
Right HPV, cm3 0.25 (0.03) 0.28 (0.03) 35.16 <0.001
v CSF, cm3 3.52 (1.59) 3.22 (1.50) 28.72 <0.001
WMH, cm3 0.85 (2.64) 0.73 (2.01) 9.33 <0.001
  1. For z scores, the mean is 0 and the standard deviation is 1. For scaled scores, the mean is 10 and the standard deviation is 3. Data are missing for seven participants. BNT Boston naming test, BPF brain parenchymal fraction, HP hippocampal volume, vCSF ventricular cerebrospinal fluid, WMH white matter hyperintensities