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Table 4 Characteristics (mean (SD)) of participants above and below selected cutoffs

From: Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers

< −1.0 SD on two memory tests

Below cutoff

Above cutoff

F

P

(n = 196)

(n = 291)

Category fluency, z score

−0.40 (1.11)

0.38 (1.28)

14.23

<0.001

BNT, scaled score

10.09 (3.62)

12.55 (3.56)

25.60

<0.001

Trails B/A ratio, z score

0.01 (1.14)

−0.45 (0.82)

7.18

<0.001

BPF

0.81 (0.03)

0.82 (0.03)

49.02

<0.001

Left HP volume, cm3

0.23 (0.03)

0.27 (0.03)

44.83

<0.001

Right HP volume, cm3

0.25 (0.03)

0.28 (0.03)

41.03

<0.001

v CSF, cm3

3.52 (1.59)

3.19 (1.49)

28.99

<0.001

WMH, cm3

0.63 (1.34)

0.87 (2.70)

8.69

<0.0001

< −1.5 SD on one memory test

Below cutoff

Above cutoff

F

P

(n = 264)

(n = 223)

Category fluency, z score

−0.31 (1.11)

0.51 (1.31)

14.23

<0.001

BNT, scaled score

10.47 (3.71)

12.85 (3.45)

24.00

<0.001

Trails B/A ratio, z score

−0.11 (1.08)

−0.45 (0.83)

3.81

0.005

BPF

0.81 (0.03)

0.82 (0.02)

44.99

<0.001

Left HPV, cm3

0.24 (0.03)

0.27 (0.03)

27.38

<0.001

Right HPV (cm3)

0.25 (0.03)

0.29 (0.03)

33.42

<0.001

v CSF, cm3

3.53 (1.63)

3.07 (1.40)

28.94

<0.001

WMH, cm3

0.82 (2.31)

0.72 (2.19)

8.89

<0.001

< −2.0 SD on one memory test

Below cutoff

Above cutoff

F

P

(n = 174)

(n = 313)

Category fluency, z score

−0.42 (1.05)

0.33 (1.31)

11.61

<0.001

BNT, scaled score

10.19 (3.71)

12.32 (3.60)

19.22

<0.001

Trails B/A ratio, z score

−0.08 (1.12)

−0.37 (0.89)

3.40

0.009

BPF

0.81 (0.03)

0.82 (0.03)

45.07

<0.001

Left HPV, cm3

0.23 (0.03)

0.26 (0.03)

31.79

<0.001

Right HPV, cm3

0.25 (0.03)

0.28 (0.03)

35.16

<0.001

v CSF, cm3

3.52 (1.59)

3.22 (1.50)

28.72

<0.001

WMH, cm3

0.85 (2.64)

0.73 (2.01)

9.33

<0.001

  1. For z scores, the mean is 0 and the standard deviation is 1. For scaled scores, the mean is 10 and the standard deviation is 3. Data are missing for seven participants. BNT Boston naming test, BPF brain parenchymal fraction, HP hippocampal volume, vCSF ventricular cerebrospinal fluid, WMH white matter hyperintensities