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Table 2 Variables predicting AD in addition to < −1.5 SD on one episodic memory test

From: Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers

   Block by block Final model
Predictor Nagelkerke’s R 2 Odds ratio Confidence interval P Odds ratio Confidence interval P
Block 1: main predictors .396       
Age   1.000 1.0, 1.0 0.997 0.982 0.9, 1.0 0.454
Education   0.993 0.9, 1.1 0.870 0.994 0.9, 1.1 0.893
Sex   1.028 0.6, 1.7 0.917 1.025 0.6, 1.8 0.935
Mini-mental state exam   0.729 0.6, 0.8 <0.001 0.811 0.7, 1.0 0.010
< −1.5 SD on one test   22.061 7.7, 63.0 <0.001 12.390 4.2, 36.8 <0.001
Block 2: non-memory tests .425       
Category fluency   0.834 0.6, 1.1 0.163 0.854 0.7, 1.1 0.252
Boston naming test   0.937 0.9, 1.0 0.109 0.937 0.9, 1.0 0.127
Trails B/A ratio   1.314 1.0, 1.7 0.033 1.216 0.9, 1.6 0.164
Block 3: biomarkers .482       
Apolipoprotein E ε4        0.036
Apolipoprotein E ε4 (1 allele)      1.767 1.0, 3.2 0.055
Apolipoprotein E ε4 (2 alleles)      2.853 1.2, 7.0 0.021
Total hippocampal volume      0.015 0.0, 1.7 0.081
Brain parenchymal fraction      0.000 0.0, 0.2 0.030
White matter hyperintensity      1.025 0.9, 1.1 0.654
Ventricular cerebrospinal fluid      1.043 0.9, 1.3 0.687