Block by block | Final model | ||||||
---|---|---|---|---|---|---|---|
Predictor | Nagelkerke’s R 2 | Odds ratio | Confidence interval | P | Odds ratio | Confidence interval | P |
Block 1: main predictors | .396 | ||||||
Age | 1.000 | 1.0, 1.0 | 0.997 | 0.982 | 0.9, 1.0 | 0.454 | |
Education | 0.993 | 0.9, 1.1 | 0.870 | 0.994 | 0.9, 1.1 | 0.893 | |
Sex | 1.028 | 0.6, 1.7 | 0.917 | 1.025 | 0.6, 1.8 | 0.935 | |
Mini-mental state exam | 0.729 | 0.6, 0.8 | <0.001 | 0.811 | 0.7, 1.0 | 0.010 | |
< −1.5 SD on one test | 22.061 | 7.7, 63.0 | <0.001 | 12.390 | 4.2, 36.8 | <0.001 | |
Block 2: non-memory tests | .425 | ||||||
Category fluency | 0.834 | 0.6, 1.1 | 0.163 | 0.854 | 0.7, 1.1 | 0.252 | |
Boston naming test | 0.937 | 0.9, 1.0 | 0.109 | 0.937 | 0.9, 1.0 | 0.127 | |
Trails B/A ratio | 1.314 | 1.0, 1.7 | 0.033 | 1.216 | 0.9, 1.6 | 0.164 | |
Block 3: biomarkers | .482 | ||||||
Apolipoprotein E ε4 | 0.036 | ||||||
Apolipoprotein E ε4 (1 allele) | 1.767 | 1.0, 3.2 | 0.055 | ||||
Apolipoprotein E ε4 (2 alleles) | 2.853 | 1.2, 7.0 | 0.021 | ||||
Total hippocampal volume | 0.015 | 0.0, 1.7 | 0.081 | ||||
Brain parenchymal fraction | 0.000 | 0.0, 0.2 | 0.030 | ||||
White matter hyperintensity | 1.025 | 0.9, 1.1 | 0.654 | ||||
Ventricular cerebrospinal fluid | 1.043 | 0.9, 1.3 | 0.687 |