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Table 2 Variables predicting AD in addition to < −1.5 SD on one episodic memory test

From: Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers

  

Block by block

Final model

Predictor

Nagelkerke’s R 2

Odds ratio

Confidence interval

P

Odds ratio

Confidence interval

P

Block 1: main predictors

.396

      

Age

 

1.000

1.0, 1.0

0.997

0.982

0.9, 1.0

0.454

Education

 

0.993

0.9, 1.1

0.870

0.994

0.9, 1.1

0.893

Sex

 

1.028

0.6, 1.7

0.917

1.025

0.6, 1.8

0.935

Mini-mental state exam

 

0.729

0.6, 0.8

<0.001

0.811

0.7, 1.0

0.010

< −1.5 SD on one test

 

22.061

7.7, 63.0

<0.001

12.390

4.2, 36.8

<0.001

Block 2: non-memory tests

.425

      

Category fluency

 

0.834

0.6, 1.1

0.163

0.854

0.7, 1.1

0.252

Boston naming test

 

0.937

0.9, 1.0

0.109

0.937

0.9, 1.0

0.127

Trails B/A ratio

 

1.314

1.0, 1.7

0.033

1.216

0.9, 1.6

0.164

Block 3: biomarkers

.482

      

Apolipoprotein E ε4

      

0.036

Apolipoprotein E ε4 (1 allele)

    

1.767

1.0, 3.2

0.055

Apolipoprotein E ε4 (2 alleles)

    

2.853

1.2, 7.0

0.021

Total hippocampal volume

    

0.015

0.0, 1.7

0.081

Brain parenchymal fraction

    

0.000

0.0, 0.2

0.030

White matter hyperintensity

    

1.025

0.9, 1.1

0.654

Ventricular cerebrospinal fluid

    

1.043

0.9, 1.3

0.687