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Table 1 Variables predicting AD in addition to < −1 SD on two episodic memory tests

From: Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers

   Block by block Final model
Predictor Nagelkerke’s R 2 Odds ratio Confidence interval P Odds ratio Confidence interval P
Block 1: main predictors 0.422       
Age   1.031 1.0, 1.1 0.146 1.006 1.0, 1.1 0.812
Education   0.987 0.9, 1.1 0.780 0.989 0.9, 1.1 0.830
Sex   1.131 0.7, 2.0 0.662 1.163 0.6, 2.1 0.626
Mini-mental state exam   0.712 0.6, 0.8 <0.001 0.763 0.6, 0.9 0.001
< −1 SD on two tests   12.845 6.7, 24.6 <0.001 8.082 3.9, 16.8 <0.001
Block 2: non-memory tests 0.439       
Category fluency   0.853 0.7, 1.1 0.227 0.869 0.7, 1.1 0.314
Boston naming test   0.944 0.9, 1.0 0.167 0.948 0.9, 1.0 0.227
Trails B/A ratio   1.215 0.9, 1.6 0.130 1.142 0.9, 1.5 0.342
Block 3: biomarkers 0.490       
Apolipoprotein E ε4        0.031
Apolipoprotein E ε4 (1 allele)      1.797 1.0, 3.3 0.055
Apolipoprotein E ε4 (2 alleles)      2.992 1.2, 7.3 0.016
Total hippocampal volume      0.081 0.0, 12.3 0.326
Brain parenchymal fraction      0.000 0.0, 27.9 0.123
White matter hyperintensity      1.085 1.0, 1.2 0.121
Ventricular cerebrospinal fluid      1.135 0.9, 1.4 0.240