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Table 1 In vivo distribution of I-125–labeled drugs measured in blood, heart, brain, and injection regions

From: Central delivery of iodine-125–labeled cetuximab, etanercept and anakinra after perispinal injection in rats: possible implications for treating Alzheimer’s disease

  Blood AC, %ID/g Heart AC, %ID/g Brain AC, %ID/g Perispinal region AC, %ID/g Dorsal tail vein AC, %ID/g
Cetuximab      
  Perispinal      
   Rat 1 2.06 0.39 4.05 0.06
   Rat 2 0.19 0.05 0.01 17.15
  Dorsal tail vein      
   Rat 3 5.24 1.61 0.10 0.46
Etanercept      
  Perispinal      
   Rat 4 0.14 0.04 0.01 1.10
   Rat 5 0.10  0.03 0.01 0.93
  Dorsal tail vein      
   Rat 6 2.98 0.91 0.08 0.20
Anakinra      
  Perispinal      
   Rat 7 0.30 0.11 0.06 10.86
   Rat 8 0.16 0.07 0.02 7.31
  Dorsal tail vein      
   Rat 9 0.37 0.19 0.04 0.15
  1. Abbreviations: AC average concentration, %ID/g percentage injected dose per gram of tissue