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Table 1 In vivo distribution of I-125–labeled drugs measured in blood, heart, brain, and injection regions
| Blood AC, %ID/g | Heart AC, %ID/g | Brain AC, %ID/g | Perispinal region AC, %ID/g | Dorsal tail vein AC, %ID/g | |
|---|---|---|---|---|---|
| Cetuximab | |||||
| Perispinal | |||||
| Rat 1 | 2.06 | 0.39 | 4.05 | 0.06 | – |
| Rat 2 | 0.19 | 0.05 | 0.01 | 17.15 | – |
| Dorsal tail vein | |||||
| Rat 3 | 5.24 | 1.61 | 0.10 | – | 0.46 |
| Etanercept | |||||
| Perispinal | |||||
| Rat 4 | 0.14 | 0.04 | 0.01 | 1.10 | – |
| Rat 5 | 0.10 | 0.03 | 0.01 | 0.93 | – |
| Dorsal tail vein | |||||
| Rat 6 | 2.98 | 0.91 | 0.08 | – | 0.20 |
| Anakinra | |||||
| Perispinal | |||||
| Rat 7 | 0.30 | 0.11 | 0.06 | 10.86 | – |
| Rat 8 | 0.16 | 0.07 | 0.02 | 7.31 | – |
| Dorsal tail vein | |||||
| Rat 9 | 0.37 | 0.19 | 0.04 | – | 0.15 |
