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Table 1 Demographic, neuropsychological, and CSF data for the sample

From: Brain metabolism and cerebrospinal fluid biomarkers profile of non-amnestic mild cognitive impairment in comparison to amnestic mild cognitive impairment and normal older subjects

  CG (n = 30) aMCI (n = 33) naMCI (n = 32) p value (two-tailed)
    Multiple comparison
Age (years)a 69.5 (6.4) 72.6 (5.5) 69.8 (5.8) 0.065
Gender (female/male)b 24/6 20/13 23/9 0.23
Education (years)a 12.9 (4.9) 9.2 (4.0) 11.8 (4.3) 0.018
CG × aMCI
(p = 0.017)
GDSc 1.5 (1.3) 1 (1.4) 0.113
GAIc 6.6 (4.3) 5.1 (4.1) 0.181
Hypertensionb 19 (57 %) 15 (46 %) 0.388
Diabetes mellitusb 7 (21 %) 3 (9 %) 0.186
MMSEa 29.0 (1.0) 27.6 (1.5) 27.8 (1.9) 0.000
CG × aMCI and naMCI
(p <0.003)
CSF Aβc,d 704 (248) 918 (430) 0.044
CSF tauc,d 258 (125) 247 (110) 0.84
CSF p-tauc,d 44 (12) 43 (14) 0.97
CSF p-tau/Aβ proteind   0.07 (0.05) 0.06 (0.04) 0.13
WMH visual scaleb [24] 0: 06 (20 %) 0: 04 (12 %) 0: 04 (13 %) 0.525
  I: 13 (43 %) I: 16 (49 %) I: 18 (56 %)
  II: 08 (27 %) II: 09 (27 %) II: 10 (31 %)
  III: 03 (10 %) III: 04 (12 %) III: 0 (0 %)
  1. Data presented as mean (standard deviation)
  2. aAnalysis of variance (post-hoc test: Bonferroni)
  3. bChi-square test
  4. c t test
  5. dSubsample of 54 subjects (26 naMCI patients and 28 aMCI patients), Mann–Whitney test (not normally distributed)
  6. aMCI amnestic mild cognitive impairment, amyloid beta, CG control group, CSF cerebrospinal fluid, GAI Geriatric Anxiety Scale, GDS Geriatric Depression Scale (15 items), MMSE Mini-Mental State Examination, naMCI nonamnestic mild cognitive impairment, p-tau phosphorylated-tau, WMH white matter hyperintensities