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Table 7 Ordinal logistic regression models showing the relationships between hippocampal pathologies and severity of clinical dementia

From: Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles

  Model 1 Model 2 Model 3
  OR CI p value OR CI p value OR CI p value
GVD-IR 2.12 (1.23–3.64) 0.007 1.30 (0.69–2.44) 0.422 1.31 (0.68–2.54) 0.417
NFT-IR 2.47 (1.45–4.22) 0.001 1.61 (0.84–3.10) 0.152 3.16 (1.48–6.71) 0.003
  1. Model 1 controlling for age and sex; model 2 additionally controlling for NFT and NP; model 3 additionally controlling for TDP-43 and amyloid deposits
  2. CI confidence interval, GVD granulovacuolar degeneration, IR immunoreactive, NFT neurofibrillary tangles, NP neuritic plaques, OR odds ratio, TDP-43 Tar-DNA binding protein 43