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Table 7 Ordinal logistic regression models showing the relationships between hippocampal pathologies and severity of clinical dementia

From: Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles

 

Model 1

Model 2

Model 3

 

OR

CI

p value

OR

CI

p value

OR

CI

p value

GVD-IR

2.12

(1.23–3.64)

0.007

1.30

(0.69–2.44)

0.422

1.31

(0.68–2.54)

0.417

NFT-IR

2.47

(1.45–4.22)

0.001

1.61

(0.84–3.10)

0.152

3.16

(1.48–6.71)

0.003

  1. Model 1 controlling for age and sex; model 2 additionally controlling for NFT and NP; model 3 additionally controlling for TDP-43 and amyloid deposits
  2. CI confidence interval, GVD granulovacuolar degeneration, IR immunoreactive, NFT neurofibrillary tangles, NP neuritic plaques, OR odds ratio, TDP-43 Tar-DNA binding protein 43
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Alzheimer's Research & Therapy

ISSN: 1758-9193