Skip to main content
Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

Fig. 2

Possible markers for microglial phenotyping in human brains. Scheme to illustrate different markers that could be used for identifying different microglial phenotypes in human brains. Data show some markers that have been applied from more than one study. We include markers whose function is suggestive of polarity (e.g., CD200R, CD33 and TREM-2) but not proven with published data for human microglia. CCL C–C chemokine ligand, CD200R CD200 receptor, CSF-1R colony-stimulating factor-1 receptor, IBA-1 ionized calcium binding adaptor molecule-1, IFN-γ interferon gamma, IL interleukin, LPS lipopolysaccharide, TGF transforming growth factor, TNF tumor necrosis factor, TREM-2 triggering receptor expressed by myeloid cells-2

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193