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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

Fig. 1

Various morphologies of microglia in human brain sections. Progressive changes in morphology of HLA-DR-expressing microglia in a pathology-rich section from an AD case. HLA-DR-expressing microglia can be found with various activation morphologies ranging from a highly ramified to c moderately hypertrophic to e highly activated with enlarged cell body and processes. b, d Intermediate changes in morphology. Sections were stained using antibody LN3 (1:1,000 dilution; Abcam, Cambridge, MA, USA) using nickel-enhanced diaminobenzidine peroxidase immunohistochemistry and counterstained with neutral red

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