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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Association of cognitive function with glucose tolerance and trajectories of glucose tolerance over 12 years in the AusDiab study

Fig. 2

Adjustment for insulin sensitivity and inflammation in models of glycaemia and processing speed (SDMT) at 12 years for participants aged 25–59 years with no known diabetes. a Association after adjustment for insulin sensitivity (HOMA-%S) for males and females (25–59 years). b Model-predicted SDMT as a function of sex and quintiles of insulin sensitivity (low sensitivity indicates greater insulin resistance). c Association after adjustment for hs-CRP (inflammatory marker) as a function of diabetic status. d Model-predicted SDMT as a function of sex and quintiles of hs-CRP (higher values indicate greater inflammation). Error bars represent ±1 standard error of the mean. HbA1c glycated haemoglobin, HOMA-2 Homeostatic Model Assessment, hs-CRP high-sensitivity C-reactive protein, IFG impaired fasting glucose, IGT impaired glucose tolerance, New Diab new diabetes SDMT Symbol–Digit Modalities Test

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