Microglial proliferation in
human Alzheimer’s disease brain. Representative images of the detection of Ki67 in microglial cells (Iba1+) by bright-field double immunohistochemistry (A) (DAB, brown, Iba1; AP, blue, Ki67) or double immunofluorescence (B) (Alexa 568, red, Iba1; Alexa 488, green, Ki67) from the temporal cortex of a patient with Alzheimer’s disease. Images adapted from . Iba1, ionized calcium-binding adaptor molecule 1.