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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer’s disease patients and healthy controls

Figure 1

Hybrid immunoaffinity-mass spectrometry characterization of plasma neurogranin. (A) Hybrid immunoaffinity-mass spectrometry analysis of human plasma repeatedly detected several short C-terminal peptides. *Peptides found only in plasma and not in cerebrospinal fluid or brain tissue. ‡Nonspecific binding of other plasma proteins to magnetic beads. (B) A cluster of peaks roughly corresponding to the mass of full-length neurogranin (Ng) is present in plasma. *Peak corresponding to the theoretical mass of full-length Ng (7,618 Da). m/z, Mass-to-charge ratio.

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Alzheimer's Research & Therapy

ISSN: 1758-9193