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Table 1 Characteristics of the study population a

From: Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study

Characteristics

Overall (N = 367)

AD (n = 160)

Non-AD (n = 207)

P -value b

Age (yr), mean (SD)

65.9 (10.7)

67.9 (9.7)

64.5 (11.2)

0.002

Women, n (%)

190 (51.9)

97 (60.6)

93 (45.2)

0.003

MMSE, mean (SD)

22.2 (61.1)

20.3 (6.1)

23.6 (5.6)

<0.001

CSF biomarkers (pg/ml), mean (SD)

    

Total tau

445.4 (334.8)

660.5 (349.5)

279.2 (202.9)

<0.001

pTau-181

62.8 (37.2)

89.7 (38.7)

42.0 (17.6)

<0.001

Aβ42

863.6 (357.3)

668.5 (297.3)

1,014.5 (325.9)

<0.001

Aβ40

15,426.6 (8,630.6)

16,383.6 (8,761.3)

14,686.9 (8,475.4)

0.06

Aβ 42/40

0.068 (0.047)

0.047 (0.022)

0.084 (0.054)

<0.001

  1. aAβ, Amyloid-beta; AD, Alzheimer’s disease; CSF, Cerebrospinal fluid; MMSE, Mini Mental State Examination; SD, Standard deviation. bBy χ2 test or analysis of variance.