TY - JOUR AU - Dumurgier, Julien AU - Schraen, Susanna AU - Gabelle, Audrey AU - Vercruysse, Olivier AU - Bombois, Stéphanie AU - Laplanche, Jean-Louis AU - Peoc’h, Katell AU - Sablonnière, Bernard AU - Kastanenka, Ksenia V. AU - Delaby, Constance AU - Pasquier, Florence AU - Touchon, Jacques AU - Hugon, Jacques AU - Paquet, Claire AU - Lehmann, Sylvain PY - 2015 DA - 2015/06/01 TI - Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study JO - Alzheimer's Research & Therapy SP - 30 VL - 7 IS - 1 AB - The cerebrospinal fluid (CSF) biomarkers amyloid-β (Aβ), tau and phosphorylated tau (p-tau181) are now used for the diagnosis of Alzheimer’s disease (AD). Aβ40 is the most abundant Aβ peptide isoform in the CSF, and the Aβ 42/40 ratio has been proposed to better reflect brain amyloid production. However, its additional value in the clinical setting remains uncertain. SN - 1758-9193 UR - https://doi.org/10.1186/s13195-015-0114-5 DO - 10.1186/s13195-015-0114-5 ID - Dumurgier2015 ER -