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Table 5 Correlations between gray matter volume and Trail Making Test A performance in APOE ε4 carriers and non-carriers

From: Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study

Location MNI coordinates z-value Cluster-level FWE-corrected P -value
  x y z   
  TMT A
  Carriers
Right inferior frontal gyrus 38 22 16 4.28 0.01
Right precuneus 14 −51 25 3.48 0.01
Right supramarginal gyrus 57 −34 33 4.47 0.001
Left supramarginal gyrus −30 −46 37 4.37 0.01
Right superior temporal gyrus 46 −27 15 4.15 0.001
Right middle temporal gyrus 51 −61 −9 3.98 0.01
Left middle temporal gyrus 58 −19 −8 3.47 0.01
Right inferior temporal gyrus 40 −45 −27 4.54 0.001
Left inferior temporal gyrus −34 −54 −9 4.02 0.01
Right fusiform gyrus 32 −61 −5 4.13 0.001
Left fusiform gyrus −32 −52 −9 4.07 0.01
  Non-carriers
Right precuneus 8 −48 43 4.31 0.01
Right supramarginal gyrus 39 −34 37 3.36 0.01
Left supramarginal gyrus −44 −31 24 3.53 0.05
Right angular gyrus 54 −54 33 3.89 0.05
Left angular gyrus −42 −42 42 3.65 0.05
Right superior parietal lobule 39 −58 54 3.42 0.05
Right inferior parietal lobule 44 −52 48 3.39 0.05
Right middle temporal gyrus 54 −55 24 3.45 0.05
Left middle temporal gyrus −44 −45 12 3.98 0.05
  Delayed verbal recall
  Carriers
Right hippocampus 36 −30 −8 2.65 0.08b
Left hippocampus −33 −34 −8 3.49 0.01b
  Non-carriers
 
  1. aMNI, Montreal Neurological Institute. bVoxel-level family-wise error (FWE)–corrected threshold P-values within region of interest.