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Table 1 Characteristics of the sample a

From: Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer’s disease

  Total sample Low testosterone Borderline/Normal testosterone P -value
( N= 87) ( n= 44) ( n= 43)
Age, yr 75.67 (8.033) 77.24 (7.845) 74.14 (8.008) 0.075
Education level, yr 13.44 (4.324) 14.14 (3.771) 12.74 (4.746) 0.137
MMSE score 20.07 (6.789) 20.45 (5.584) 19.70 (7.839) 0.611
CDR-Global score 1.10 (.727) 1.08 (.698) 1.12 (0.762) 0.836
CDR-SOB score 6.62 (4.474) 6.38 (4.019) 6.86 (4.914) 0.624
NPI total 4.15 (2.888) 3.619 (2.408) 4.674 (3.235) 0.092
Testosterone, ng/ml 2.49 (1.046) 2.11 (.804) 3.94 (0.348) 0.000*
APOE ε4 carriers/noncarriers 54%/46% 53%/47% 54%/46% 0.909
Hyperlipidemia 65% 60% 68% 0.455
Hypertension 64% 68% 61% 0.527
Diabetes 17% 17% 17% 0.963
Obesity 19% 14% 24% 0.239
  1. aAPOE ε4, Apolipoprotein E ε4; CDR, Clinical Dementia Rating; MMSE, Mini Mental State Examination; NPI, Neuropsychiatric Inventory; SOB, Sum of Boxes. Data presented are mean (standard deviation) or percent values. *Significant P < 0.05.