Table 1 Characteristics of the sample a
From: Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer’s disease
Total sample | Low testosterone | Borderline/Normal testosterone | P -value | |
|---|---|---|---|---|
( N = 87) | ( n = 44) | ( n = 43) | ||
Age, yr | 75.67 (8.033) | 77.24 (7.845) | 74.14 (8.008) | 0.075 |
Education level, yr | 13.44 (4.324) | 14.14 (3.771) | 12.74 (4.746) | 0.137 |
MMSE score | 20.07 (6.789) | 20.45 (5.584) | 19.70 (7.839) | 0.611 |
CDR-Global score | 1.10 (.727) | 1.08 (.698) | 1.12 (0.762) | 0.836 |
CDR-SOB score | 6.62 (4.474) | 6.38 (4.019) | 6.86 (4.914) | 0.624 |
NPI total | 4.15 (2.888) | 3.619 (2.408) | 4.674 (3.235) | 0.092 |
Testosterone, ng/ml | 2.49 (1.046) | 2.11 (.804) | 3.94 (0.348) | 0.000* |
APOE ε4 carriers/noncarriers | 54%/46% | 53%/47% | 54%/46% | 0.909 |
Hyperlipidemia | 65% | 60% | 68% | 0.455 |
Hypertension | 64% | 68% | 61% | 0.527 |
Diabetes | 17% | 17% | 17% | 0.963 |
Obesity | 19% | 14% | 24% | 0.239 |