Table 4 Raw data for Figure 4 : mean amyloid-beta oligomer values in serial dilutions of AD-TBS extracts from nine brains using the 1C22/3D6B oligomer-specific ELISA
Dilutions | AD1 (pg/ml) | AD2 (pg/ml) | AD3 (pg/ml) | AD4 (pg/ml) | AD5 (pg/ml) | AD6 (pg/ml) | AD7 (pg/ml) | AD8 (pg/ml) | AD9 (pg/ml) |
|---|---|---|---|---|---|---|---|---|---|
1:2,000 | 35.0 ± 18.7 | 36.8 ± 6 | SAT | 15.5 ± 0.3 | 21.5 ± 0.8 | SAT | 8.7 ± 0.4 | 42.9 ± 5.0 | 4.7 ± 0.8 |
1:4,000 | 31.0 ± 4.8 | 17.7 ± 1.4 | SAT | 9.2 ± 0.4 | 7.1 ± 0.6 | 20.8 ± 0.05 | 3.2 ± 0.5 | 15.0 ± 0.8 | 2.9 ± 0.3 |
1:8,000 | 12.9 ± 1.6 | 8.0 ± 0.9 | SAT | 4.9 ± 0.2 | 4.9 ± 0.6 | 13.0 ± 1.16 | 2.2 ± 0.8 | 9.9 ± 0.3 | 1.3 ± 0.2 |
1:16,000 | 7.0 ± 0.5 | 5.0 ± 0.3 | SAT | 4.0 ± 0.5 | 2.2 ± 0.4 | 6.1 ± 0.31 | 0.9 ± 0.1 | 4.6 ± 0.1 | 0.8 ± 0.2 |
1:32,000 | 3.5 ± 0.3 | 2.9 ± 0.6 | 37.5 ± 2.2 | 2.5 ± 0.5 | 1.1 ± 0.1 | 3.6 ± 0.42 | 0.4 ± 0.1 | 2.5 ± 0.1 | 0.3 ± 0 |
1:64,000 | 2.0 ± 0.2 | 1.4 ± 0.1 | 17.1 ± 1.2 | 1.6 ± 0.1 | 0.6 ± 0.1 | 1.3 ± 0.1 | ND | 1.4 ± 0.2 | 0.4 ± 0 |
1:128,000 | 1.2 ± 0.3 | 0.9 ± 0.2 | 10.0 ± 1.4 | 1.4 ± 0.1 | ND | ND | 0.4 | 0.6 ± 0.1 | ND |
1:256,000 | 1.2 ± 0.4 | 0.9 ± 0.1 | 4.6 ± 0.3 | 1.0 ± 0.2 | ND | ND | ND | ND | ND |
AD-TBS (1:2,000) after 1282 + AW7 immunodepletion | N/A | N/A | N/A | N/A | ND | ND | 1.4 ± 1.5 | 0.6 ± 0.1 | 0.4 ± 0.1 |