Quantifying amyloid-beta oligomers in cerebrospinal fluid of Cohort 1 using two different monoclonal antibody pairs. No significant differences in amyloid-beta oligomer (oAβ) levels between Alzheimer’s disease subjects (AD, n = 9) and controls (CON, n = 10) were obtained with either antibody pair or without versus with 0.05% Tween 20 in the samples. Labeling as in Figures 5, 6, and 7. Lower limit of reliable quantification for 1C22/3D6 and 3B3/82E1 was 0.15 pg/ml and 0.3 pg/ml, respectively; former indicated by a dashed line. Erenna platform (Singulex, Alameda, CA, USA).