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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid

Figure 1

Comparison of antibody pairs in amyloid-beta oligomer enzyme-linked immunosorbent assay on the MSD platform. Four antibody pairs – 1C22/3D6B (A), 3B3/3D6B (B), 1C22/82E1B (C) and 3B3/82E1B (D) – were tested on the MSD platform (MSD Multi-Array; Meso Scale Discovery, Gaithersburg, MD, USA) for their ability to detect either amyloid-beta-derived diffusible ligands (ADDLs; black circles), the pro-aggregating (S26C)2 dimer (blue squares) or the aggregation-resistant dityrosine dimer (red triangles). Note that signal units on the y axis and concentrations of the amyloid-beta oligomers (pg/ml) on the x axis are on a log scale.

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Alzheimer's Research & Therapy

ISSN: 1758-9193