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Table 8 Patient characteristics at baseline: right MTA score of 0 or 1 versus 2, 3 or 4

From: The relationship of weight change trajectory with medial temporal lobe atrophy in patients with mild Alzheimer’s disease: results from a cohort study

  MTA score 0 or 1 MTA score 2, 3, 4 P
Age (year): n, median [25th -75th percentile] 17, 73.0 [72.0 - 79.0] 197, 79.0 [76.0 - 82.0] 0.003b**
Women, n (%) 9 (52.9) 123 (62.4) nsc
Social status    
 alone, n (%) 8 (47.1) 85 (44.7) nsc
 with partner, n (%) 9 (52.9) 99 (52.1)
 other*, n (%) 0 (0. 0) 6 (3.2)
CIRS (score): n, median [25th -75th percentile] 17, 5.0 [4.0 - 6.5] 197, 6.0 [4.0 - 8.0] nsb
Polypharmacy, n (%) 7 (41.2) 106 (54.1) nsc
Use of informal care, n (%) 11 (64.7) 171 (87.2) 0.022d**
Use of professional care, n (%) 5 (29.4) 94 (48.5) nsc
MMSE (score): n, median [25th -75th percentile] 17, 25.0 [22.0 - 27.5] 195, 23.0 [20.0 - 25.0] 0.026b**
Clock-drawing test (score): n, median [25th -75th percentile] 16, 3.0 [1.0 - 4.0] 177, 3.0 [2.0 - 5.0] nsb
Presence of BPS, n (%) 3 (17.7) 48 (25.0) nsd
Weight (kg): n, mean ± SD 17, 70 ± 11 197, 74 ± 12 nsa
BMI (weight/(height)2): n, median [25th -75th percentile] 15, 25.6 [21.5 - 27.0] 188, 25.9 [23.5 - 28.9] nsb
Use of ONS, n (%) 0 (0.0) 1 (0.6) nsd
Appetite    
 good, n (%) 16 (100) 154 (92.2) nsd
 poor, n (%) 0 (0.0) 13 (7.8)
Self reported weight loss, n (%) 0 (0.0) 28 (15.8) nsd
  1. *Other, that is: with son or daughter, brother or sister; **significant, that is P <0.05. aIndependent sample t test; bMann-Whitney U test; cPearson chi-square test; dFisher’s exact.
  2. MTA, medial temporal lobe atrophy; P, probability; n, number of patients; ns, not significant; CIRS, cumulative illness rating scale; MMSE, mini mental state examination; BPS, behavioral and psychological symptoms; SD, standard deviation; BMI, body mass index; ONS, oral nutritional supplement.