Skip to main content

Table 2 Reproducibility of the L-COSY method: single healthy volunteer over five separate scans

From: Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy

Molecule

Coupling

F2–F1 (ppm)

Variation (%)

Cr

N(CH3)

3.02–3.02

1

Glx-1

-CH2- CH(NH3+)

2.09–3.75

4

Glx-3

 

2.07–3.73

4

Glx-4

 

2.14–3.74

5

Glx-6

 

2.45–2.01

6

Glx-7

 

2.31–2.28

6

tCho

(CH3)3-N + −CH2-CH2-OH

4.05–4.05

2

Fucose region and Thr

-CH(OH)-CH3 CH3-CH

(F2: 4.0–4.5, F1: 1.1–1.7)

10

Phe

-CH-(aromatic)-

7.33–7.33

7

NAA

-CH3

2.00–2.00

2

Cho

(CH3)3-N + −CH2-CH2-OH

3.51–4.05

3

 

(CH3)3-N + −CH2-CH2-OH

3.20–3.20

5

mI

-CH(OH)-CH(OH)

3.63–3.29

5

  

3.55–3.55

3

  1. Abbreviations: Cho, choline; Cr, creatine; Glx 1-7, crosspeaks of glutamate + glutamine; L-COSY, localized correlated spectroscopy; mI, myo-inositol; NAA, N-acetyl aspartate; Phe, phenylalanine; ppm, parts per million; Thr, threonine. In bold are the proton groups that give rise to the crosspeak chemical shifts indicated in the third column.