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Table 2 Reproducibility of the L-COSY method: single healthy volunteer over five separate scans

From: Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy

Molecule Coupling F2–F1 (ppm) Variation (%)
Cr N(CH3) 3.02–3.02 1
Glx-1 -CH2- CH(NH3+) 2.09–3.75 4
Glx-3   2.07–3.73 4
Glx-4   2.14–3.74 5
Glx-6   2.45–2.01 6
Glx-7   2.31–2.28 6
tCho (CH3)3-N + −CH2-CH2-OH 4.05–4.05 2
Fucose region and Thr -CH(OH)-CH3 CH3-CH (F2: 4.0–4.5, F1: 1.1–1.7) 10
Phe -CH-(aromatic)- 7.33–7.33 7
NAA -CH3 2.00–2.00 2
Cho (CH3)3-N + −CH2-CH2-OH 3.51–4.05 3
  (CH3)3-N + −CH2-CH2-OH 3.20–3.20 5
mI -CH(OH)-CH(OH) 3.63–3.29 5
   3.55–3.55 3
  1. Abbreviations: Cho, choline; Cr, creatine; Glx 1-7, crosspeaks of glutamate + glutamine; L-COSY, localized correlated spectroscopy; mI, myo-inositol; NAA, N-acetyl aspartate; Phe, phenylalanine; ppm, parts per million; Thr, threonine. In bold are the proton groups that give rise to the crosspeak chemical shifts indicated in the third column.